Biofunctional Assessment and Interventional Treatment of Coronary Inflammation guided by Magnetic Resonance Imaging

磁共振成像引导下冠状动脉炎症的生物功能评估及介入治疗

基本信息

项目摘要

Magnetic resonance imaging (MRI) is steadily emerging its diagnostic potential in cardiovascular disease. Furthermore, MRI has entered the stage for interventional application due to technical developments, absence of ionizing radiation, and superior soft tissue contrast compared to fluoroscopy. In this proposal, we build a consortium of interventional cardiologists with expertise in molecular imaging and medical physicists with an acknowledged track-record of cutting edge MR-sequence, catheter-tracking and coil development. We aim to enable real-time assessment of coronary plaque inflammation with molecular imaging, intravascular high-resolution MRI of the coronary vessel wall, as well as interventional real-time MR-guided coronary intervention with implantation of scaffolds or new generation drug eluting stents (DES) to “seal” the inflamed site. We ultimately envision fully MR-guided investigation and interventional treatment of inflamed and therefore potentially vulnerable coronary lesions.
磁共振成像(MRI)在心血管疾病中的诊断潜力正在稳步显现。此外,由于技术的发展、无电离辐射以及与荧光透视相比具有上级软组织对比度,MRI已进入介入应用阶段。在该提案中,我们建立了一个由具有分子成像专业知识的介入心脏病专家和具有公认的尖端MR序列、导管跟踪和线圈开发跟踪记录的医学物理学家组成的联盟。我们的目标是通过分子成像、冠状动脉血管壁的血管内高分辨率MRI以及植入支架或新一代药物洗脱支架(DES)以“密封”炎症部位的介入性实时MR引导冠状动脉介入治疗,实现冠状动脉斑块炎症的实时评估。我们最终设想完全MR引导的调查和介入治疗的炎症,因此潜在的脆弱冠状动脉病变。

项目成果

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Professor Dr. Michael Bock其他文献

Professor Dr. Michael Bock的其他文献

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{{ truncateString('Professor Dr. Michael Bock', 18)}}的其他基金

Improvement of Novel Imaging Technologies to Study Anatomical and Pathological Morphology in Ancient Human Remains: Terahertz Imaging and Spectroscopy and Magnetic Resonance Imaging
改进新型成像技术来研究古代人类遗骸的解剖和病理形态:太赫兹成像和光谱以及磁共振成像
  • 批准号:
    277686684
  • 财政年份:
    2015
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Real-time reconstruction for MR Angiography
磁共振血管造影的实时重建
  • 批准号:
    142132699
  • 财政年份:
    2009
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Tumor Segmentation and Tumor Probability Analysis with Convolutional Neural Networks: Novel Strategies for Individualized Radiation Therapy of Head&Neck Cancer
卷积神经网络的肿瘤分割和肿瘤概率分析:头部个体化放射治疗的新策略
  • 批准号:
    443978314
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Temporal dynamics of monocyte migration after myocardial infarction with 19F-MRI
19F-MRI 心肌梗死后单核细胞迁移的时间动态
  • 批准号:
    492563001
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
    Research Grants

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