Artery-selective time-resolved and quantitative measurements of intracranial arteries by hybrid 4D flow Arterial Spin Labeling Magnetic Resonance Angiography

通过混合 4D 流动脉自旋标记磁共振血管造影对颅内动脉进行动脉选择性时间分辨和定量测量

• 批准号: 418126342
• 负责人: Dr. Thomas Lindner
• 金额: --
• 依托单位: Klinik für Radiologie und Neuroradiologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2019
• 资助国家: 德国
• 起止时间: 2018-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/418126342?language=en
• 关键词: Artery; selective; time; resolved; quantitative

The aim of this work is to combine the novel developed selective Arterial Spin Labeling (ASL) technique with the experimental neuro 4D-flow phase contrast angiography technique. Both experimental MRI techniques have to be validated and optimized in order to be used in neuro applications. By this, it should be made possible to visualized individual arteries in the brain which not only show morphological changes but also quantitative measures can be performed. Thereby vascular diseases are expected to be visualized in more detail and following this, diagnostic confidence should increase. This is for example important in the early detection of rupture risk in aneurysms.

本工作的目的是将新开发的选择性动脉自旋标记（ASL）技术与实验性神经4D血流相位对比血管造影技术相结合。这两种实验性MRI技术都必须经过验证和优化才能用于神经应用。通过这种方式，应该能够可视化大脑中的单个动脉，其不仅显示形态学变化，而且可以进行定量测量。因此，预计血管疾病将被更详细地可视化，并且在此之后，诊断信心应该增加。例如，这在动脉瘤破裂风险的早期检测中是重要的。