中耳腔の経粘膜換気作用の検討

中耳腔经粘膜通气检查

• 批准号: 12770955
• 负责人: 山本 裕
• 金额: $ 1.02万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Encouragement of Young Scientists (A)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-12770955/
• 关键词: 中耳; 経粘膜換気; 表面積; 体積; 圧トランスジューサ; ブタ

研究成果当科聴神経腫瘍患者12例を対象として側頭骨CTの画像情報をコンピュータに移入し、画像解析ソフトウェアを用いて中耳含気腔の表面積と体積を計測した。その結果、中耳含気腔容積は平均3.87±3.51ml、表面積は49.19±40.89cm^2、両者間の相関係数は0.96、回帰関数はY=5.664+11.248×Xとなり、強い1次相関を認めることがわかった。その後、慢性中耳炎手術症例2耳を用いて計測の信頼性を検証した。外耳道を密閉後マイクロシリンジで容積負荷を行い、それに伴う圧上昇を圧トランスジューサーで計測し実測値の中耳含気腔容積を求めた。その結果CTでの計測値と実測値はよく一致しCTでの計測の信頼性が確認された。今後の研究の展望1.対象も例数をさらに増やし計測データの信頼性を増す。2.笑気を用いた全身麻酔下での耳手術中に笑気拡散による中耳圧変化を計測し経粘膜換気能と中耳含気腔の体積、表面積との関係を検証する。

Research results: 12 cases of patients with neurological tumors in the Department of Neurology, CT image information of the side of the skull, and information on the results The surface area and volume of the middle ear containing cavities were measured using the image analysis method. According to the results, the average volume of the middle ear containing cavity was 3.87±3.51ml, the surface area was 49.19±40.89cm^2, and the difference between the two The correlation number is 0.96, the number of return points is Y=5.664+11.248×Xとなり, and the strong correlation is 1 time. After the surgery, the case of chronic otitis media 2 ear surgery was used to measure the symptoms of the disease. After the external auditory canal is sealed, the pressure of the volume load can be increased after the external auditory canal is sealed. The volume of the middle ear containing cavity is determined by measuring the volume of the middle ear cavity. The result of the CT measurement is consistent with the measurement result of the CT measurement. Prospects for future research 1. Measurement of the number of cases and the reliability of the test results. 2. During ear surgery, the pressure of the middle ear can be measured and the pressure of the middle ear can be measured under general anesthesia. The relationship between the volume and surface area of ​​the middle ear containing cavities and the volume and surface area of ​​the middle ear can be verified.