Viral ecO-evOlutionary Dynamics of wild and domestic pOllinatOrs under global change

全球变化下野生和家养传粉媒介的病毒生态进化动态

基本信息

项目摘要

Pollinators and pollination underpin ecosystem and human health but they face multiple threats from global change. Anthropogenic modification of landscape floral resources by land-use and alien species may nutritionally stress pollinators and alter their abundance and species interactions. This can magnify disease risk, especially from RNA viruses that, due to high mutation and recombination rates, rapidly adapt to environmental changes and novel hosts, often leading to emerging infectious diseases. However, major knowledge gaps exist on the potential for global change to drive virus host shifts and emergent pandemic viruses that could lead to managed and wild pollinator losses. Recent evidence suggests viral co-infection across a spectrum of pollinators. Nevertheless how global change pressures shape pollinator disease risk by modifying host nutrition, viral adaptation to alternative hosts, the buffering effects of species diversity and the role of particular species or habitats as transmission hubs, remains poorly understood. VOODOO aims to discover how the eco-epidemiological dynamics of plant-pollinator-virus interactions from individual to community levels are modulated by changes to the availability and quality of nutritional (floral) resources driven by intensive agriculture, alien plant species, and urbanisation. Using ecological sampling and high-resolution molecular analyses (quantitative and strand-specific PCR), we will quantify tripartite (plant-pollinator-virus) networks in different landscapes and use network and eco-epidemiological modelling to reveal disease hubs and dynamics across organisms and habitats. We will couple this with semi-field experiments examining transmission pathways and laboratory selection experiments (incorporating NGS) testing viral fitness/adaptation in known and alternative host species subjected to field-realistic nutritional stress treatments. We will engage with diverse societal actors to integrate complementary knowledge on decision-making for risk management and implementation to assure sustainable societal outcomes.
传粉者和授粉是生态系统和人类健康的基础,但它们面临着全球变化的多重威胁。土地利用和外来物种对景观植物资源的人为改变可能会对传粉者造成营养压力,并改变它们的丰度和物种间的相互作用。这可能会放大疾病风险,特别是来自RNA病毒的风险,由于高突变和重组率,RNA病毒迅速适应环境变化和新宿主,通常导致新出现的传染病。然而,在全球变化驱动病毒宿主转移和可能导致管理和野生传粉者损失的新流行病毒的潜力方面存在重大知识差距。最近的证据表明,在一系列传粉媒介中存在病毒共感染。然而,全球变化压力如何通过改变宿主营养、病毒对替代宿主的适应、物种多样性的缓冲作用以及特定物种或生境作为传播枢纽的作用来塑造传粉媒介疾病的风险,仍然知之甚少。VOODOO旨在发现从个体到社区水平的植物-传粉者-病毒相互作用的生态流行病学动态如何通过集约农业,外来植物物种和城市化驱动的营养(花卉)资源的可用性和质量的变化来调节。利用生态采样和高分辨率分子分析(定量和链特异性PCR),我们将量化不同景观中的三方(植物-传粉者-病毒)网络,并利用网络和生态流行病学建模来揭示生物体和栖息地的疾病中心和动态。我们将这与半现场实验检查传输途径和实验室选择实验(结合NGS)测试病毒的健身/适应已知和替代的宿主物种进行现场现实的营养压力治疗。我们将与不同的社会参与者合作,整合风险管理和实施决策的互补知识,以确保可持续的社会成果。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Professor Dr. Robert Paxton其他文献

Professor Dr. Robert Paxton的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Professor Dr. Robert Paxton', 18)}}的其他基金

Emergence and host switching in insect picorna-like viruses: wild and managed bee species as a model host community
昆虫小核糖核酸样病毒的出现和宿主转换:野生和管理蜂种作为模型宿主群落
  • 批准号:
    288222923
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:
    Priority Programmes
A comparative approach to the fecundity/longevity trade-off across two origins of eusociality in the bees
蜜蜂两种真社会性起源的繁殖力/寿命权衡的比较方法
  • 批准号:
    276413230
  • 财政年份:
    2015
  • 资助金额:
    --
  • 项目类别:
    Research Units
Populationsstruktur von Wildbienen und ihren Parasiten (Hymenoptera: Apoidea) - analysiert mittels molekulargenetischer und populationsökologischer Methoden
野生蜜蜂及其寄生虫(膜翅目:Apoidea)的种群结构 - 使用分子遗传学和种群生态方法进行分析
  • 批准号:
    5118296
  • 财政年份:
    1998
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Molekularbiologische Untersuchungen über Fortpflanzungskonflikte bei sozialen Bienen
群居蜜蜂生殖冲突的分子生物学研究
  • 批准号:
    5271244
  • 财政年份:
    1996
  • 资助金额:
    --
  • 项目类别:
    Research Grants

相似国自然基金

面向功能ECO的不等价逻辑抽取方法研究
  • 批准号:
    61204047
  • 批准年份:
    2012
  • 资助金额:
    28.0 万元
  • 项目类别:
    青年科学基金项目
中外生态村(Eco-village)的比较研究与实践
  • 批准号:
    50678112
  • 批准年份:
    2006
  • 资助金额:
    28.0 万元
  • 项目类别:
    面上项目

相似海外基金

Eco-evolutionary dynamics of seasonally mobile systems
季节性移动系统的生态进化动力学
  • 批准号:
    NE/Y000684/1
  • 财政年份:
    2024
  • 资助金额:
    --
  • 项目类别:
    Research Grant
BoCP-Implementation: Eco-evolutionary dynamics of rewilding: Real-time genetic monitoring of large-mammal community reassembly
BoCP-实施:野化的生态进化动力学:大型哺乳动物群落重组的实时基因监测
  • 批准号:
    2225088
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Continuing Grant
RAPID: Eco-evolutionary dynamics of host-parasite interactions in a novel environment
RAPID:新环境中宿主-寄生虫相互作用的生态进化动力学
  • 批准号:
    2323185
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Standard Grant
Eco-evolutionary dynamics of parallel climate-driven range shifts in the wild
野外气候驱动范围变化的平行生态进化动力学
  • 批准号:
    EP/X023362/1
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Fellowship
How well can we predict future changes in biodiversity using machine learning? Experiments in an eco-evolutionary testbed.
我们如何利用机器学习来预测生物多样性的未来变化?
  • 批准号:
    2890191
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Studentship
Developing and testing an eco-evolutionary theory for range limits
开发和测试范围限制的生态进化理论
  • 批准号:
    2230806
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Standard Grant
Can eco-evolutionary theories explain outcomes of microbiome coalescence
生态进化理论能否解释微生物组合并的结果
  • 批准号:
    DP230101448
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Discovery Projects
Eco-evolutionary dynamics of parasitism mediated through variance in host fitness
通过宿主适应性差异介导的寄生生态进化动力学
  • 批准号:
    2310874
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Standard Grant
Collaborative Research: ORCC: Understanding Organismal Behavioral Responses to Climate Change to Forecast Eco-evolutionary Dynamics of Albatrosses Populations
合作研究:ORCC:了解生物体对气候变化的行为反应以预测信天翁种群的生态进化动态
  • 批准号:
    2222058
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Standard Grant
Investigating the role of sexual conflict in parasitoid- host eco-evolutionary dynamics
研究性冲突在寄生生物-宿主生态进化动力学中的作用
  • 批准号:
    2883381
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
    Studentship
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了