High-throughput incubation and imaging system for crystal growth

用于晶体生长的高通量孵化和成像系统

• 批准号: 429649016
• 金额: --
• 依托单位: Medizinische Hochschule Hannover (MHH)
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2020
• 资助国家: 德国
• 起止时间: 2019-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/429649016?language=en
• 关键词: throughput; incubation; imaging; system; crystal

A high-throughput system is required for the documentation, analysis and optimization of crystallization experiments and the sensitive identification of protein crystals. The system will allow the automated tracking of crystallization experiments over a period of several weeks at a constant temperature. The nucleation and growth of protein crystals will be reliably documented, even under difficult optical conditions, in the presence of aggregated material and salt crystals. The system will support a variety of plate formats. A modular design of the system based on exchangeable standard components is preferred.

对于结晶实验的记录、分析和优化以及对蛋白质晶体的灵敏鉴定，需要一个高通量系统。该系统将允许在恒定温度下对几周内的结晶实验进行自动跟踪。蛋白质晶体的成核和生长将被可靠地记录下来，即使在困难的光学条件下，在聚集物质和盐晶体的存在下也是如此。该系统将支持多种板材格式。最好采用基于可交换标准部件的系统模块化设计。