课题基金 / 基金详情

SPECIFIC INTERACTION OF MODEL-tRNA AND AMINO ACIDS

SPECIFIC INTERACTION OF MODEL-tRNA AND AMINO ACIDS
模型-tRNA 和氨基酸的特异性相互作用
批准号:
03452306
负责人:
SHIMIZU Mikio
金额:
$3.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1991
资助国家:
日本
项目状态:
已结题
起止时间:
1991 至 1993

项目摘要

项目成果

SHIMIZU Mikio的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
To discuss the origin of genetic code, the possibility of a specific interaction between RNA and amino acid was studied. Identity determinants of 20 kinds of tRNAs in E.coli are at first investigated, constructing various tRNA mutant transcripts by using the T7 RNA polymerase. Anticodon bases and discriminator nucleotide are found to be the important determinant in most of tRNAs. Consequently, a small RAN composed of anticodon arm and acceptor stem was constructed and its aminoacylation activity was studied enzymatically. Only minihelix or microhelix in some cases works well. Next time, more active amino acids should be used for this type of investigations.
期刊论文(62)
专著(0)
科研奖励(0)
会议论文
N.Nameki: "E.coli tRNA ^<Asp> Recognition Mechanism" B.B.R.C.189. 856-862 (1993)
N.Nameki:“大肠杆菌 tRNA ^<Asp> 识别机制”B.B.R.C.189。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
K.Tamura et al: "Identify Detcemonants of tRNA^<Ang> and tRNA^<Lys> in E.cobi" Nucleia Acids Res.
K.Tamura 等人:“鉴定大肠杆菌中 tRNA^<Ang> 和 tRNA^<Lys> 的检测因子”Nucleia Acids Res。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
T.Hasegawa et al: "Identify Dertcemnants of E.cobi tRNA^<Thn>" Biochen,Bioply Res Communication.
T.Hasekawa 等人:“鉴定大肠杆菌 tRNA^<Thn> 的Dertcemnants”Biochen,Bioply Res Communication。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
清水外: "The Role of Anticoem Bases us The Discrimination nuclisties" J.Mol.Biol.35. 436-443 (1992)
Shimizu Gai:“Anticoem 基础对我们歧视核主义者的作用”J.Mol.Biol.35 (1992)。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
31
    Experimental Approach for the Molecular Recognition Mechanism of Amino Acids by Complex of Four Nucleotides on tRNA
    • 批准号:
      58420054
    • 项目类别:
      Grant-in-Aid for General Scientific Research (A)
    • 资助金额:
      $19.71万
    • 财政年份:
      1983
    • 负责人:
      SHIMIZU Mikio
    • 依托单位:
    海外基金