Allotments of gustatory functions in the chorda tympani (CT), great superficial petrosal nerve (GSP) and lingual nerve (LN).
Allotments of gustatory functions in the chorda tympani (CT), great superficial petrosal nerve (GSP) and lingual nerve (LN).
批准号:
03454434
负责人:
KASAHARA Yasuo
金额:
$4.22万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1991
资助国家:
日本
项目状态:
已结题
起止时间:
1991 至 1993
中文摘要
为了阐明CT.GSP或LN的功能特性,在大鼠、仓鼠和豚鼠上进行了神经反应记录和行为实验(条件性味觉厌恶范式)。GSP对仓鼠的蔗糖味道的辨别具有重要意义。GSP的反应特征不同于GT,3.软腭味蕾与舌味蕾的受体位置或转导机制不同。LN5的辣椒素、薄荷醇敏感纤维非常少。软腭上的味蕾不仅对甜味物质有很高的反应能力,而且对其他味道也有不同的反应特性。GSP和/或CT双侧切开后,厌恶程度明显降低,其影响顺序为GSP+CT>;GSP()SY.gtoreq()CT>;Sham。这些实验结果表明,GSP在调节甜味信息方面起着重要作用。
英文摘要
To clarify the functional properties of CT.GSP or LN, neural response recording and behavioral experiments (conditioned taste aversion paradigm) were performed in the rats, hamsters and guinea pigs.From the results of these serial experiments indicated that1. GSP is important for the discrimination of sucrose taste in the hamster2. response characteristics for GSP were different from GT,3. the different receptor site or transduction mechanisms in taste buds on the soft palate from those on the tongue4. there were very very few Capsaicin, Menthol sensitive fibers in the LN5. taste buds on the soft palate have not only high responsiveness for sweet substance but also different response properties for other taste6. the degree of the aversion was significantly decreased when the GSP and/or CT were sectioned bilaterally.The order of the sectioning effects was GSP+CT > GSP (〕SY.gtoreq.〔) CT > Sham. From the results of these experiments suggest the GSP plays an important role for mediating sweet taste information.
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Harada,S.: "A method to acknowledge pulse train in biological signals by a microcomputer system." Chemical Senses. 18. 335 (1993)
Harada,S.:“一种通过微计算机系统确认生物信号中的脉冲序列的方法。”
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榎元 勝治: "ラット口腔内味蕾の分布と形態の発育に伴う変化." 歯科基礎医学会雑誌. 35. 116 (1993)
Katsuharu Enomoto:“发育过程中大鼠口腔味蕾的分布和形态的变化。”日本基础牙科医学会杂志 35. 116 (1993)
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Kohriyama, H.: "Characteristics of the chorda tympani responses to gustatory stimuli in the guinea-pig" Chem.Senses. 18. 329 (1993)
Kohriyama, H.:“豚鼠鼓索对味觉刺激的反应特征”Chem.Senses。
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Harada,S.: "Decrease of taste discrimination ability for sucrose after bilateral sections of the greater superficial petrosal nerve." Proceedings of the 25th Japanese Symposium on Taste and Smell. 25. 305-308 (1991)
Harada,S.:“岩浅神经双侧切片后,蔗糖味觉辨别能力下降。”
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Kohriyama,H.: "Characteristics of the chorda tympani responses to gustatory stimuli in the guinea-pig." Chemical Senses. 18. 329 (1993)
Kohriyama,H.:“豚鼠鼓索对味觉刺激的反应特征。”
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Changes of gustatory system through life time
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批准号:62480382
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1987
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负责人:KASAHARA Yasuo
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依托单位:
海外基金