Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs.

硫酸乙酰肝素与 VEGF 形成复合物，用于控制组织工程构建体中的血管生成。

• 批准号: DP0557863
• 负责人: Em/Prof John Whitelock
• 金额: $ 18.02万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0557863
• 关键词: Heparan; sulfate; complexes; VEGF; control

The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types of tissues being generated for clinical applications, including possible applications in the treatment of heart disease, the largest killer of people in the Western world.

这项工作将产生的国家/社区利益包括，在合成聚合物存在下产生与血管生长相关的知识，该合成聚合物看起来像体内存在的天然聚合物。 这将导致对所涉及的潜在机制的理解，这些机制可能具有与临床应用所产生的许多类型的组织的替代相关的下游效应，包括在治疗心脏病中的可能应用，心脏病是西方世界人类的最大杀手。