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Changes in bone and microvasculature surrounding dental implants in masticating-functinal condition.

咀嚼功能状态下牙种植体周围的骨和微脉管系统的变化。

基本信息

批准号：
05454536
负责人：
OHTA Yoshikuni
金额：
$ 4.54万
依托单位：
Osaka Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1993
资助国家：
日本
起止时间：
1993 至 1994
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05454536/
关键词：
Dental implant Microvascularization Repairing of wound Bone Monkey Repairing of wound

项目摘要

Sequential changes in the microvasculature and bone tissue surrounding a Ti implant coated with an anodized surface layr, which was installed in the mandibular molar area of Japanese monkeys, have been studied. These changes were surveyed both in unfunctioned and functioned conditions of the implants. Animals were kept for 20 weeks at longest after a metal crown-setting 4,8,12 weeks, respectively, following a fixture implantation, on bone-microvascular corrosion specimens by scanning electron microscopy. Under unfunctioned condition, a new bone was initially found I week after the implantation and developed to plates in 3-4 weeks. No remarkable development was seen on the new bone plate over 12 weeks. Under functioned condition, in which normal occlusion was partially obtained by setting a metal crown, movemnt of the implant was found 1 week after setting the crown immediately following the fixture implantation. 4 or 8 weeks unloaded, then 4 weeks functioned, new bone did not surround the implant yet, although bone trabeculae were thickened. 12 weeks unloaded, then funcitoned for 20 weeks, the interface of the implant was tightly surrounded by a compactioned bone which adhered to the pre-exising compact bone. Ti material coated with an anodized surface layr may promote the development of new bone plate integrating the implant interface. Time for setting the superstructure may be suggested to be during 9-12 weeks after fixture installation.

本文研究了日本猴下颌磨牙区植入表面涂有阳极氧化涂层的钛种植体周围微血管和骨组织的连续变化。这些变化在植入物的无功能和功能条件下进行了调查。分别于金属冠固定4、8、12周后，将动物放置于骨微血管腐蚀标本上，扫描电镜观察，最长放置20周。在无功能的情况下，植入后1周开始发现新骨，并在3-4周内发育成板状。12周后，新骨板未见明显发育。在功能状态下，通过安装金属冠部分获得正常咬合，在固定装置植入后立即安装冠后1周发现植入物移动。术后4 ~ 8周未加载，术后4周功能恢复，骨小梁增厚，但种植体周围未见新骨形成。卸载12周，功能恢复20周，种植体界面被松质骨紧密包围，松质骨与松质骨紧密结合。钛材料表面经阳极氧化处理可促进与种植体界面结合的新骨板的形成。上部结构的安装时间建议在固定装置安装后的9-12周内。