The role of raphe nuclei in regulating sexual behavior in rats.

本实验研究了中缝背核和中缝正中核在调节雌性和雄性大鼠性行为中的作用，结果表明，中缝背核而不是中缝正中核在调节雄性大鼠脊柱前凸行为（雌性性行为）中起抑制作用。对脊柱前凸的抑制作用是由中缝背核中的多巴胺能神经元产生的，并由从中缝背核腹前区到前脑的神经纤维发出。此外，中缝背核的功能不依赖于外侧隔的另一个抑制系统。GABA能神经元对脊柱前凸的抑制依赖于中缝背核的功能，中缝正中核对雄性大鼠射精行为具有抑制作用。雌性大鼠中缝正中核对雄性性行为的调节也有抑制作用。但中缝背核对男性性行为的调节不是必需的。

In this experiment, the role of the dorsal raphe nucleus and the median raphe nucleus in regulating female and male sexual behavior was investigated in rats.In the conclusion, the dorsal raphe nucleus but not median raphe nucleus plays an inhibitory role in regulation of lordosis behavior (female sexual behavior) in male rats. The inhibition for lordosis is exerted by serotonergic neurons in the dorsal raphe nuclues and is sent by the neural fibers which leave from the anterovental area of the nucleus to the forebrain. Furthermore, the function of the dorsal raphe nuclues is independent on an another inhibitory system in the lateral septum. The inhibition of lordosis by GABAergic neurons is dependent on the function of the dorsal raphe nucleus.The median raphe nuclues has an inhibitory role in regulating ejaculatory behavior in male rats. In female rats, the median raphe nucleus also exert inhibitory influence in ragualtion for male sexual behavior. However, the dorsal raphe nucleus is not essentian for the regualtion of male sexual behavior.