MODIFICATION OF NYCTHEMERAL VARIATIONS IN BODY CORE TEMPERATURE AFTER DAILY EXERCISE AT A FIXED TIME

每日固定时间锻炼后夜间身体核心温度变化的修正

• 批准号: 05670064
• 负责人: SHIDO Osamu
• 金额: $ 1.34万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05670064/
• 关键词: body temperature regulation; heat stress; training; circadian rhythm; adaptation; 運動

The present study was conducted to examine how daily exercise for several hours at a fixed time modifies the pattern of day-night variations in body core temperature and behavior in rats. Spontaneous wheel running was adopted as a model of exercise to avoid any artificial stress on rats.1. Male Wistar rats were acclimated to cages with a running wheels. Then, the running time of rats were limited to the first or last 3 or 6 h of the dark phase. After a 2-week activity restriction, the rats were again allowed access to the wheel freely. Wheel revolutions of rats during the period corresponding to the previous running time significantly increased after the activity restriction.2. Male Wistar rats were kept in cages with a running wheel and allowed access to the wheel for 6 h in the last half of the dark phase. After a 3-week exercise period, they were denied to run in the wheel. Their body core temperature significantly increased for 2-3 hours in the last half of the dark phase.The results suggest that, in rats, voluntary running limited to a fixed time daily alters the pattern of nycthemeral variations in body core temperature and locomotor activity, i.e., body core temperature and running activity increase during the period when the rats were previously allowed to exercise.

本研究的目的是研究每天固定时间几个小时的锻炼如何改变大鼠体内核心温度和行为的昼夜变化模式。采用自发轮跑作为运动模型，避免对大鼠造成人为应激。 1．雄性 Wistar 大鼠适应了带有跑轮的笼子。然后，将大鼠的奔跑时间限制在黑暗阶段的前3或后3或6小时。两周的活动限制后，再次允许大鼠自由使用轮子。限制活动后大鼠前次跑步时间对应的轮转数显着增加。 2．将雄性 Wistar 大鼠关在带有跑轮的笼子中，并在黑暗阶段的后半部分允许其接触跑轮 6 小时。经过三周的锻炼后，他们被拒绝开车跑步。在黑暗阶段的后半段，它们的身体核心温度在2-3小时内显着升高。结果表明，在大鼠中，每天限制在固定时间的自愿跑步改变了身体核心温度和运动活动的夜间变化模式，即在之前允许大鼠运动期间，身体核心温度和跑步活动增加。

项目成果

Sakurada et al.: "Changes in hypothalamic temperature of rats after daily exposure to heat at a fixed time." Pflugers Arch.429. 291-293 (1994)

Sakurada 等人：“每天在固定时间暴露于高温后，大鼠下丘脑温度的变化。”

Shido et al.: "Day-night changes in body temperature and feeding activity in heat-acclimated rats." Physiol. Behav.55. 935-939 (1994)

Shido 等人：“热适应大鼠体温和进食活动的昼夜变化。”

Shido et al.: "Shifts of thermoeffector thresholds in heat-acclimated rats." J.Physiol. (Lond.). 483. 491-494 (1995)

Shido 等人：“热适应大鼠中热效应器阈值的变化。”

Shido,O.: "Shifts of thermoeffector thresholds in heat‐acclimated rats." Journal of Physiology(London). 483巻. 491-494 (1994)

Shido, O.：“热适应大鼠的热效应器阈值的变化。”生理学杂志（伦敦）483. 491-494（1994）。

Shido,O.: "Day-night changes of body temperature and feeding activity in heat-acclimated rats." Physiology and Behavior. (in press). (1993)

Shido,O.：“热适应大鼠体温和摄食活动的昼夜变化。”