Epithelium migration in cholesteatoma surgery

通过对302耳胆脂瘤患者术后复发、残留胆脂瘤、上皮化及感染情况的评估，对鼓膜及外耳道上皮细胞移行情况进行了研究。保留胆脂瘤基质的所有耳均有正常的移行模式。在未保留胆脂瘤基质的耳中观察到缓慢或无迁移。我们的研究结果表明，保留胆脂瘤基质的一期鼓室成形术是预防胆脂瘤残留和复发以及获得干燥和安全的耳的最佳手术方法。

Epithelium migration of tympanic membrane and external auditory canal in 302 ears with cholesteatoma was studied by the post-operative evaluation of the recurrence, residual cholesteatma, epithelization and infection. A normal migration pattern was present in all ears in which cholesteatoma matrix was preserved. A slow or no migration was observed in the ear in which cholesteatoma matrix was not preserved.Our findings of the normal migration in ears with preservation of the cholesteatoma matrix leads us to the conclusion that the one stage tympanoplasty with preservation of cholesteatoma matrix is the best operative method for preventing residual and recurrent cholesteatoma and for achieving a dry and safety ear.