Study on dental alloys to clarify the mechanism of allergy

为了阐明过敏的机制，在口腔内进行了电极电位的功能测量。该方法包括测量口腔内各种牙科合金的金属离子渗透。所测合金为Co、Cr、Ni和Sn，被认为是高过敏率的牙科材料，并与低过敏率的Au和Au- ag - pd牙科合金进行比较。该实验涉及4名男性受试者，他们在前磨牙或磨牙区域都有一个完整的铸造冠。功能状态包括3种类型的测量，1)休息位时，2)侧移时，3)含pH3.75溶液时。结果表明：Ni-Cr合金在静置状态下电位变化范围为-63.9 ~ 325.7mV，在横向运动状态下电位变化范围为-82.0 ~ 365.3mV，在溶液作用下电位变化范围为-92.4 ~ 396.7mV。Co-Cr合金在静置状态下电位变化范围为-134.3 ~ 4.115mV，在横向运动状态下电位变化范围为-181.7 ~ 434.0mV，在溶液作用下电位变化范围为-279.3 ~ 427.7mV。Ag合金在静置状态下电位变化范围为-154.8 ~ 288.4mV，在横向运动状态下电位变化范围为-191.2 ~ 308.7mV，在溶液作用下电位变化范围为-234.2 ~ 376.8mV。在静置状态下，Au-Ag-Pd合金的电位变化范围为+51.4 ~ 135.0mV，在横向运动状态下，电位变化范围为+51.8 ~ 138.3mV，在溶液作用下电位变化范围为-27.0 ~ 238.4mV。对于Au合金，静止状态下电位变化范围为+25.0 ~ 103.9mV，横向运动时电位变化范围为+21.4 ~ 132.0mV，溶液作用下电位变化范围为-35.6 ~ 226.2mV。综上所述，口腔材料的电极电位功能测量显示金属离子的渗透。

In order to clarify the mechanism of allergy, functional measurements of the electrode potential within the oral cavity were undertaken. This method involved measuring the metallic ion penetration of the various dental alloys within the oral cavity. The alloys measured were Co, Cr, Ni, and Sn which are considered to be dental materials having a high allergy rate, and were in turn compared to the low allergy rate dental alloys of Au and Au-Ag-Pd. The experiment involved 4 male subjects having either a full cast crown on the premolar or molar region. The functional condition included 3 type of measurements, 1) during the rest position, 2) lateral movement, and 3) with a pH3.75 solution in the mouth. Results showed that for Ni-Cr alloy, the electric potential changed from -63.9--325.7mV during rest position, -82.0--365.3mV during lateral movement, and -92.4--396.7mV with the solution. For Co-Cr alloy, the electric potential changed from -134.3--4.115mV during rest position, -181.7--434.0mV during lateral movement, and -279.3--427.7mV with the solution. Ag alloy showed the electric potential to change from -154.8--288.4mV during rest position, -191.2--308.7mV during lateral movement, and -234.2--376.8mV with the solution. The electric potential for Au-Ag-Pd alloy changed from +51.4--135.0mV during rest position, +51.8--138.3mV during lateral movement, and -27.0--238.4mV with the solution. For Au alloy, the electric potential changed from +25.0--103.9mV during rest position, +21.4--132.0mV during lateral movement, and -35.6--226.2mV with the solution . In conclusion, it can be said that the functional measurments of electrode potential for the dental materials showed penetration of metallic ions.