NONINVASIVE THERMOMETRY USING INTRACAVITARY MICROWAVE RADIOMETRY

使用腔内微波辐射测量的无创测温

• 批准号: 06452447
• 负责人: MIZUSHINA Shizuo
• 金额: $ 3.84万
• 依托单位: SHIZUOKA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06452447/
• 关键词: Noninvasive thermometry; Intracavitary thermometry; Microwave radiometry; Phantom experiment; Temperature resolution; Temperature profile in body; Radiometric weighting function; Antenna-tissue coupling 3D analysis; 非侵襲温度計測法; 組織温度プロフィル; アンテナ-生体結

(1) A newly designed 1.2GHz radiometer receiver has been developed and incorporated into a 5-frequency-band radiometer system previously developed at Shizuoka University. A new feedback control circuit, in which a stepping motor was replaced with a 12-bit D/A converter, was installed in the 1.2GHz receiver to control the temperature of the reference temperature noise source. With this modification, the brightness temperature resolution of 0.036K was achieved at a 5-second integration time, where the theoretical value was 0.032K.(2) A dielectric-filled (epsilon_r=60) waveguide antenna having a 4.6cm x 4.6cm aperture has been developed to achieve the depth of measurement sensitivity of about 4cm. The electromagnetic coupling of this antenna to a homogeneous tissue medium and to a four-layred tissue medium consisting of bolus, skin, fat and muscle has been analyzed in 3 dimensions using the modal analysis and the finite-difference time-domain method. From the 3D field analysis results, ra … More diometric weighting functions were derived for the realistic model of the antenna-tissue system. A temperature profile retrieval algorithm has also been developed using the new weighting functions.(3) Experiments were performed using this antenna and a 5-band radiometer system to measure the temperature profile in an agar phantom (agar powder : 4%, NaCl : 0.24%, NaN_3 : 0.4%, distillled water : 95.36%). The temperature profile obtained by the radiometric method agreed well with probe measurement results, demonstrating the validity of the radiometric method. The resolution (2sigma interval) of tissue temperature measurement was 0.2ﾟC at 2cm, 0.7ﾟC at 3cm, 1.6ﾟC at 4cm from the phantom surface.(4) An intracavitary antenna has been developed. Experiments were made by inserting this antenna in an agar phantom. The antenna was used both for the 2.45GHz heating and the radiometric temperature measurement at 2.4GHz in a time division scheme. The single-band radiometric measurement was made to estimate the maximum temperature in tissue. The radiometric estimation gave higher values than the highest temperatures by measured by probes by about 0.5ﾟC. Less

(1)一种新设计的1.2GHz辐射计接收机已被开发出来，并被纳入了以前在静冈大学开发的5频段辐射计系统。在1.2GHz接收机中，采用12位D/A转换器代替步进电机，采用反馈控制电路对参考温度噪声源进行温度控制。在5秒积分时间内，获得了0.036K的亮温分辨率，而理论值为0.032K。(2)研制了一种孔径为4.6cm × 4.6cm的介质填充波导天线（λ_r=60），其深度测量灵敏度约为4cm。该天线的电磁耦合到一个均匀的组织介质和一个四层的组织介质组成的团，皮肤，脂肪和肌肉已被分析在3维使用模态分析和时域有限差分法。从三维场分析结果来看， ...更多信息 针对天线-组织系统的实际模型导出了距离加权函数。利用新的加权函数还开发了一种温度廓线反演算法。(3)利用该天线和5波段辐射计系统进行了实验，测量了琼脂模体（琼脂粉：4%，NaCl：0.24%，NaN 3：0.4%，蒸馏水：95.36%）中的温度分布。辐射法得到的温度分布与探针测量结果吻合较好，证明了辐射法的有效性。组织温度测量的分辨率（2sigma间隔）在距离体模表面2cm处为0.2 ° C，3cm处为0.7 ° C，4cm处为1.6 ° C。(4)研制了一种腔内天线。通过将该天线插入琼脂体模中进行实验。该天线用于2.45GHz的加热和在2.4GHz的辐射温度测量在一个时分方案。采用单波段辐射测量法估计组织内的最高温度。辐射估计值比探测器测量的最高温度高出约0.5摄氏度。少

项目成果

S.Mizushina et al.: "Multifrequency Microwave Radiometry for Medical Applications" Proc. 1996 Int. Symp. on Antennas and Propagation (Invited Paper). (1996)

S.Mizushina 等人：“医疗应用的多频微波辐射测量”Proc。

H,Ohba,……,and S,Mizushina: Institute of Electronics, Information and Communication Engineers Transactions. E78-C. 1071-1081 (1995)

H，Ohba，……，和 S，Mizushina：电子、信息和通信工程师协会交易 E78-1081（1995）。

S.Mizoshiri,...,and S.Mizushina: "Computation of the Field Distribution Generated by a Rectangular Aperture in a Four‐Layered Lossy Dielectric Medium" Institute of Electronics, Information and Communication Engineers Transactions. E78‐B. 851-858 (1995)

S.Mizoshiri，...，和 S.Mizushina：“四层有损介电介质中矩形孔径生成的场分布的计算”电子、信息和通信工程师协会交易 E78-858。 (1995)

S.Mizushina et al.: "Recent Trends in Medical Microwave Radiometry" Institute of Electronics, Information and Communication Engineers Transactions. E78-B. 789-798 (1995)

S.Mizushina 等人：“医用微波辐射测量的最新趋势”，电子、信息和通信工程师研究所交易。

S.Mizushina et al.: "Recent Trends in Medical Microwave Radiometry" Institute of Electronics, Information and Communication Engineers Transactions. E78‐B. 789-798 (1995)

S. Mizushina 等人：“医学微波辐射测量的最新趋势”，电子、信息和通信工程师协会 E78-798 (1995)。