Non-Invasive Measurement of Temperature Profiles in Biological Object by Microwave Fadiometry

微波辐射度测量法无创测量生物物体的温度分布

• 批准号: 01460160
• 负责人: MIZUSHINA Shizuo
• 金额: $ 3.33万
• 依托单位: Shizuoka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-01460160/
• 关键词: thermometry; non-invasive thermometry; body temperature distribution; temperature profile; tissue temperature resolution; microwave; radiometry; multi-frequency radiometry; 組織温度測定分解能; 体温計測; 無侵襲温度測定; ラジオメ-タ; 多周波; 温度プロフィル測定; マイクロ波ラジオメトリ

The body temperature is a physical parameter that provides the body with the fundamental background condition for its life, activities and functions. Temperature measured at the axilla, for example, is usually taken as the body temperature. Actually, it is not uniform in a body. It takes different values at various parts of body and it also changes with the time, reflecting changes in physiological conditions, for instance. However, the knowledge of temperature distribution in a living body is limited due to the lack of non-invasive temperature measurement technique. In the hyperthermia treatment of cancer, tissue temperatures at several points in the treatment region are measured invasively by inserting thermometer probes, such as thermocouples. Development of non-invasive temperature measurement techniques is strongly desired.The microwave radiometry is investigated to develop a non-invasive temperature measurement technique. In our method, the brightness temperature of a biological … More object is measured at five different microwave frequencies to obtain a set of data, and a temperature-versus-depth profile is retrieved from the set of data. Results obtained during the 1989-1990 period can be summarized as follows : (1) It was shown theoretically and experimentally that the radiometric temperature measurement was possible from above a water-filled bolus which was required for the surface cooling during the heating for hyperthermic treatment, (2) a method was developed using the Monte Carlo technique to calculate the precision of tissue temperature measurement along the temperature profile, (3) it became possible to calculate the precision of tissue temperature measurement from the brightness temperature resolution of the radiometer, (4) numerical simulation indicated that the precision of about +/-0.4 k at 2 cm and about +/-0.7 k at 4 cm from surface was to be expected at an integration time of 5 seconds for a new radiometer which was under construction in our laboratory. Less

体温是为人体的生命、活动和功能提供基本本底条件的物理参数。例如，腋下测量的温度通常被认为是体温。实际上，它在身体里并不是统一的。它在身体的不同部位取值不同，也会随着时间的推移而变化，例如反映生理条件的变化。然而，由于缺乏非侵入性的温度测量技术，人们对活体内温度分布的了解有限。在癌症的热疗中，通过插入温度计探头，如热电偶，对治疗区域内几个点的组织温度进行侵入性测量。非侵入式测温技术的发展迫在眉睫，为了开发一种非侵入性测温技术，对微波辐射测温技术进行了研究。在我们的方法中，生物…的亮度温度在五个不同的微波频率上测量更多的对象以获得一组数据，并且从该组数据中检索温度-深度分布。-1990年期间获得的结果可概括如下：(1)从理论和实验上证明，在热疗加热过程中表面冷却所需的充满水的团状物上可以进行辐射温度测量，(2)用蒙特卡罗技术计算组织温度沿温度分布的测量精度，(3)根据辐射计的亮度温度分辨率计算组织温度测量的精度，(4)数值模拟表明，本实验室正在研制的新型辐射计在距地面2 cm处的积分时间为5s时，其精度可达+/-0.4k，在距地面4 cm处的精度可达+/-0.7k。较少

项目成果

S.Mizushina,Y.Hamamura,M.Matsuda,T.Sugiura: "A Method of Solution for a Class of Inverse Problems involving Measurement Errors and its Application to Medical Microwave Radiometry" 1989 IEEE MTTーS International Microwave Symposium Digest. 171-174 (1989)

S.Mizushina、Y.Hamamura、M.Matsuda、T.Sugiura：“涉及测量误差的一类反问题的解决方法及其在医学微波辐射测量中的应用”1989 IEEE MTT-S 国际微波研讨会文摘 171-。 174 (1989)

S. Mizushina, Y. Hamamura, M. Matsuda, T. sugiura: "A Method of Solution for a Class of Inverse Problems Involving Measurement Errors and its Application to Medical Microwave Radiometry" 1989 IEEE MTT-S Int. Microwave Symp. Digest. 171-174 (1989)

S. Mizushina、Y. Hamamura、M. Matsuda、T. sugiura：“涉及测量误差的一类反问题的解决方法及其在医学微波辐射测量中的应用”1989 IEEE MTT-S Int。

浜村 良紀: "マイクロ波ラジオメ-タ輝度温度測定値からの体内温度逆推定法" 電子情報通信学会論文誌. 841-850 (1989)

Yoshinori Hamamura：“通过微波辐射计亮度温度测量来逆估计体内温度”，电子、信息和通信工程师学会会刊 841-850 (1989)。

S.Mizushina,Y.Hamamura,M.Matsuda,T.Sugiura: "Microwave Rediometry and Temperature Profiling" Proceedings of the progress In Electromagneties Research. 485-486 (1989)

S.Mizushina、Y.Hamamura、M.Matsuda、T.Sugiura：“微波辐射测量和温度分析”电磁学研究进展论文集。

S. Mizushina: "Microwave Systems for Non-invasive Thermometry with Emphasis on Temperature Profiling" Procs. of the 5th Int. Symp. on Hyperthermic Oncology,. Vol. 2,. 742-743 (1989)

S. Mizushina：“用于非侵入式测温的微波系统，重点是温度分析”Procs。