Breaking selective constraints: is Hsp90 a capacitor of evolutionary change?
Breaking selective constraints: is Hsp90 a capacitor of evolutionary change?
批准号:
DP0557494
负责人:
Prof Carla Sgro
金额:
$47.57万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2005
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2005-10-31 至 2010-12-31
中文摘要
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英文摘要
Gene action and expression can be modulated by genetic mechanisms. If a general mechanism controlling gene expression exists that can be easily manipulated it has the potential to allow animal and plant breeders to quickly produce and select for new characters of agricultural importance without relying on transgenics and long-term breeding programs. It would also assist in the development of tools for identifying and detecting genes that increase susceptibility to human diseases, such as cancer, that are only expressed under certain conditions environmental. I intend to determine whether the protein Hsp90 represents a general mechanism controlling gene expression.
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