A new method of measurement of intracranial pressure using a ultrasonic probe

一种利用超声波探头测量颅内压的新方法

• 批准号: 61480308
• 负责人: KUCHIWAKI Hiroji
• 金额: $ 4.1万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1987
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-61480308/
• 关键词: Intracranial Pressure; Transcranial; Ultrasonic Pulse Echo; 干渉波形; 頭蓋内圧; 超音波信号発生器; 超音波

Interfering ultrasonic(UT) waves reflected from thin layers, such as dura mater or subarachnoid space, are found to yield considerable information about thr region of reflection. These phenomena were demonstrated by the reflection coefficient(RC) of UT waves.A spike/ burst pulser transmits UT waves to a newly devised UT probe (5 MHz) which is connected to receiver system. UT - waves from the thin layers in oscilloscope are selected by gate circuit and continuousyl recorded through DC-amplifier during which data of RC by a trigger of electrocardiography are analyzed with computor system (Maximum Entropy Method).In experimentally raised ICP changes of UT wave- forms well corresponded to those of epidural pressure transducer. The thickness of the thin layers decreased gradually with linear correlation in range of intracranial pressure( 50 - 700 mmH20 ) with hydrostatic or balloon inflation.In clinical study we recorded the UT wave-form of intracranial pressure on the scalp in the area of bone defect as well as normal skull. Rapid responses in changing on intracranial pressure by UT probe are also observed at neck compression or hyperventilation.The transcranial UT-pulse echo method and their signal processing by computor are found to be valuable for determining information about intracranial pressure.

从硬脑膜或蛛网膜下腔等薄层反射的干涉超声波可提供有关反射区域的大量信息。利用超声波的反射系数（RC）验证了这一现象，并利用尖脉冲/猝发脉冲发生器将超声波发射到与接收系统相连的新型超声探头（5 MHz）上。用门电路从示波器的薄层中选择UT波，经直流放大器连续记录，用计算机系统（最大熵法）分析由心电图触发的RC数据，在实验中得到的UT波形的ICP变化与硬膜外压力传感器的ICP变化有很好的对应关系。颅内压在50 ~ 700 mmH ~（20）范围内，随着充液或充气囊，薄层厚度逐渐减小，并呈线性关系。在颈部受压或过度换气时，UT探头对颅内压的变化也有快速反应，经颅UT脉冲回波法及其计算机信号处理对测定颅内压信息有一定的价值。

项目成果

伊藤淳樹, 口脇清治, 長坂昌登, 木野本武久, 高田宗春, 石原仁, 景山直樹: 医学のあゆみ. 138. 529-530 (1986)

Jun. Ito, Ki. Kuchiwaki，Masato Nagasaka，Takehisa Kinomoto，Muneharu Takada，Hitoshi Ishihara，Naoki Kageyama：医学史。 138. 529-530 (1986)

伊藤淳樹, 口脇清治, 長坂昌登, 石原仁, 景山直樹, 佐々間宣光, 小倉幸夫: 超音波医学. 14. 111-118 (1987)

Jun. Ito, Ki. Kuchiwaki，Masato Nagasaka，Hitoshi Ishihara，Naoki Kageyama，No. Sasama，Yukio Ogura：超声医学。

Hiroji Kuchiwaki, Jyunki Itoh, Hitoshi Ishiguri, Kazuhiko Andoh, Yukio Ogura, Nobumitsu Sakuma, Toshio Takishita.: "An approach to noninvasive analysis of intracranial pressure(ICP) using a ultrasonic probe." Intracranial Pressure VII. VII. (1988)

Hiroji Kuchiwaki、Jyunki Itoh、Hitoshi Ishiguri、Kazuhiko Andoh、Yukio Ogura、Nobumitsu Sakuma、Toshio Takishita.：“使用超声波探头进行颅内压 (ICP) 无创分析的方法。”

Jyunki Itoh, Hiroji Kuhciwaki, Masato Nagasaka, Hitoshi Ishiguri, Naoki Kageyama, Nobumitu Sakuma, Sachio Ogura: "A basic study of continuous monitorings of intracranial pressure using a ultrasonic probe - a preliminary report from experimental model-" Ja

Jyunki Itoh、Hiroji Kuhciwaki、Masato Nagasaka、Hitoshi Ishiguri、Naoki Kageyama、Nobumitu Sakuma、Sachio Ogura：“使用超声波探头连续监测颅内压的基础研究 - 实验模型的初步报告 -” Ja

口脇博治: 超音波医学.

口胁宏二：超声医学。