Establishment of methods for assessing peripheral sensory perception response to the environmental stimuli and its application.

为了建立振动触觉感知、温度感知和触摸压力感知等外周感觉的测量方法，我们进行了基础实验，然后将这些方法应用于使用振动工具的工人的外周感觉干扰评估。在这项研究中，这些新方法使我们能够测量振动触觉感知、温度感觉和两点辨别的阈值。研究结果如下：1)对小型激振器在2 ~ 400 Hz范围内产生的振动刺激，在短期内定量测量了振动触觉感知阈值的加速度水平。2)在固定于指尖的探针的恒温上升过程中，利用放大器测量热阈值，受试者感知到的温升水平使我们能够评估热阈值。在上午2点到10点的范围内，使用我们设计和制造的两点鉴别试验探针定量测量了更多的nt鉴别。4)健康被试的振动触觉感知阈值随年龄的增长在整个频率范围内呈上升趋势，在100 Hz、200 Hz等高频率范围内呈上升趋势。5)健康受试者的温度感觉阈值和两点辨别阈值也随年龄增长而升高。6)临床应用表明，这些方法可用于以麻木、疼痛和雷诺现象为主诉的被试周围感觉障碍的分期划分。这些外周感觉反应的新方法使我们能够测量振动触觉、温度感觉和触摸压力感觉，不仅有助于观察外周感觉的老化效应，而且有助于外周感觉障碍的分类。我们计划利用本研究建立的方法来阐明热条件、振动和噪声以及这些因素的综合影响对周围感觉知觉的影响。少

In order to establish the methods for measuring peripheral sensory perception such as vibro-tactile perception, temperature sensation and touch-pressure sensation, we have carried out fundamental experiments, and then we have applied these methods for assessment of peripheral sensory disturbance of workers using vibrating tools. In this study, these new methods enabled us to measure the threshold of vibro-tactile perception, temperature sensation and two-point discrimination. The results obtained in this study were as follows:1) The acceleration level of the vibro-tactile perception threshold was measured quantitatively in a short-term for the vibration stimuli from 2 to 400 Hz which were generated from a small vibration excitor.2) In the constant temperature rise of the probe, which was attached to the fingertip, using the amplifier for measuring the thermal threshold, the level of the temperature rise, which subject perceived, enabled us to assess the thermal threshold.3) The two-poi … More nt discrimination was measured quantitatively in a range from 2 to 10 am using the probes for the two-point discrimination test which we have designed and made.4) The elevation of vibro-tactile perception threshold with aging in the whole range of frequency,which was characterized by the threshold elevation in high frequencies such as 100 Hz, 200 Hz, was observed in healthy subjects.5) The elevation of the threshold of temperature sensation and two-point discrimination with aging was also observed in healthy subjects.6) Clinical application indicated that these methods were useful for the classification of the stages in peripheral sensory disorders of the subjects who complained the symptoms such as numbness, pain and Raynaud's phenomenon.These new methods for peripheral sensory perception response enabled us to measure vibro-tactile perception, temperature sensation and touch-pressure sensation and is useful for not only the observation of the aging effects on peripheral sensory perception and but also classification ofperipheral sensory disturbance. We have a plan to elucidate the effects of thermal condition, vibration and noise and the combined effects these factors on the peripheral sensory perception using the methods which we have established in this study. Less