Neonatal learnibg Ability and Mechanism of mother-Infant Relationship Based on Fetal Memory

基于胎儿记忆的新生儿学习能力及母婴关系机制

• 批准号: 04610049
• 负责人: KODAMA Noriko
• 金额: $ 1.09万
• 依托单位: SHIGA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1992
• 资助国家: 日本
• 起止时间: 1992 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04610049/
• 关键词: fetal memory; newborn's memory; preference for mother; amniotic fluid; 新生児

This study was conducted as a series of experiments in fetal memory and learning in order to investigate the relationship between fetal memory and learning ability of the newborn, and mother-infant bond.The 2-day-old newborns of SIc : ICR mice were used as subjects. they were tested the preference to the mother's nipple, with which the taste/odor stimulus (amniotic fluid and saline) was coated, and their own mother. In stimulus preference test, newborn pups were first separated to their own mother for three hours for hunger then subjected to the test. After the mother was anesthetized with nembutal, a pup was placed in front of her. In maternal preference test, own mother of pups and alien mother were anesthtized with nembutal simultaneously. Then a pup was placed between them.The pups preferred the nipple which was coated with amniotic fluid, and their own mother. These results indicate that the 2-day-old newborn pups remember the characteristics of amniotic fluid which they experienced in the wonb in fetal period, that they choose their mother based on the memory, and that they remember the stimulus characteristics of their own mother after birth.

本研究通过一系列胎儿记忆和学习实验来探讨胎儿记忆与新生儿学习能力、母婴关系的关系。以SIc:ICR小鼠2日龄新生儿为研究对象。他们接受了对母亲乳头和自己母亲的偏好测试，乳头涂有味道/气味刺激物（羊水和盐水）。在刺激偏好测试中，新生幼崽首先因饥饿而与自己的母亲分开三个小时，然后接受测试。母亲被戊巴比妥麻醉后，一只小狗被放在她面前。在母性偏好测试中，幼仔的亲生母亲和外来母亲同时接受戊巴比妥麻醉。然后将一只幼崽放在它们之间。幼崽更喜欢涂有羊水的乳头和自己的母亲。这些结果表明，2日龄的新生幼崽能够记住胎儿时期在母胎中经历的羊水特征，并根据记忆选择母亲，并在出生后记住母亲的刺激特征。