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近年来，仿生化学受到人们的广泛关注。本研究以L-酪蛋白为基础，合成了一种新型的肽衍生物，并对其进行了功能评价，得到了以下结果：1.通过适当保护L-酪氨酸制备Boc-Tyr（OBzl）-OTce（a）。2.通过对叔丁氧羰基-OTce进行苄氧羰基甲基化反应得到叔丁氧羰基-Tyr（OCH_2CO_2Bzl）-OTce（B）。3.（B）在二氧六环中用4 N或在氢气气氛下用Pd-C处理得到H-Tyr（OCH_2CO_2Bzl）-OTce（c）或Boc-Tyr（OCH_2CO_2H）-OTce（d）。4.通过WSC-加成法偶联（c）和（d）得到二肽（e）。5. (e)以与4.6相同的方式转化为四肽（f）。使用高度稀释法合成所需的肽番（g）。7. (g)在DMSO溶液中没有显示出特异性的强氢键，由于我花了很长时间合成了所需的肽聚糖，因此不能完全表征其功能。

Recently, the biomimetic chemistry has been paid much attention. The aim of this chemistry is to mimic chemically the sophisticated functions of organisms.In this research, I investigated the synthesis of L-tyroshin-based new peptidephane ant its function evaluation.The following results were obtained. 1. Boc-Tyr(OBzl)-OTce(a) was prepared by the appropriate protection of L-tyrosine. 2. Boc-Tyr(OCH_2CO_2Bzl)-OTce(b) was obtained by the benzyloxycarbonylmenthylation of Boc-Tyr-OTce. 3. Treatment of (b) with 4N in dioxane or with Pd-C under hydrogen atmosphere afforded H-Tyr(OCH_2CO_2Bzl)-OTce(c) or Boc-Tyr(OCH_2CO_2H)-OTce(d). 4. The coupling of (c) and (d) by the WSC-additive method gave the dipeptide (e). 5. (e) was converted into the tetrapeptide (f) in the same fashion as 4.6. The desired peptidephane (g) was synthesized using the high dilution method. 7. (g) did not show the specific strong hydrogen bond in DMSO solution.Since I spent a long time to synthesize the desired peptidephane, the function of it could not be fully characterized.