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近年来，仿生化学受到了广泛的关注。这种化学的目的是用化学方法模拟生物体的复杂功能。在本研究中，我研究了基于l -酪氨酸的新型肽磷脂的合成及其功能评价。得到了以下结果：1. 在l -酪氨酸的适当保护下制备了Boc-Tyr(OBzl)-OTce(a)。2. Boc-Tyr(OCH_2CO_2Bzl)-OTce(b)由Boc-Tyr-OTce的苯氧羰基甲基化反应得到。3. (b)在二氧六烷中用4N或在氢气氛下用Pd-C处理得到H-Tyr(OCH_2CO_2Bzl)- oce (c)或Boc-Tyr(OCH_2CO_2H)- oce (d)。4. (c)和(d)通过wsc -加成法偶联得到二肽(e)。(e)以与4.6相同的方式转化为四肽(f)。采用高稀释法合成所需肽素(g)。7. (g)在DMSO溶液中未表现出特异性强氢键。由于我花了很长时间来合成我想要的肽素，所以它的功能还不能完全表征。

Recently, the biomimetic chemistry has been paid much attention. The aim of this chemistry is to mimic chemically the sophisticated functions of organisms.In this research, I investigated the synthesis of L-tyroshin-based new peptidephane ant its function evaluation.The following results were obtained. 1. Boc-Tyr(OBzl)-OTce(a) was prepared by the appropriate protection of L-tyrosine. 2. Boc-Tyr(OCH_2CO_2Bzl)-OTce(b) was obtained by the benzyloxycarbonylmenthylation of Boc-Tyr-OTce. 3. Treatment of (b) with 4N in dioxane or with Pd-C under hydrogen atmosphere afforded H-Tyr(OCH_2CO_2Bzl)-OTce(c) or Boc-Tyr(OCH_2CO_2H)-OTce(d). 4. The coupling of (c) and (d) by the WSC-additive method gave the dipeptide (e). 5. (e) was converted into the tetrapeptide (f) in the same fashion as 4.6. The desired peptidephane (g) was synthesized using the high dilution method. 7. (g) did not show the specific strong hydrogen bond in DMSO solution.Since I spent a long time to synthesize the desired peptidephane, the function of it could not be fully characterized.