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Research on Early Signs of Autistic Disorders

自闭症早期症状的研究

基本信息

批准号：
04670710
负责人：
YAMAZAKI Kosuke
金额：
$ 1.41万
依托单位：
Tokai University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1994
项目状态：
已结题

项目摘要

The following two studies were conducted for extracting the early signs of autistic disorders through observation of infant behavior :1) Evaluation utilizing a check-list :A 24-item check-list was employed for evaluation of two groups of subjects : 188 cases of autistic children (146 boys, 42 girls ; 6.7<plus-minus>3.5 years), and 261 cases of normal control subjects (133 boys, 128 girls ; 1.8<plus-minus>0.8 years). The results were classified into four levels (I-IV) by Logistic Regresion Analysis. Items in Level I were the items with highest correlation to diagnoses of autism, but behavior falling under Level IV were regarded as holding deep significance in terms of the early si2) Analysis of video tape recordings :Video recording were evaluated in 8 cases (boys, age at first visit : 2 ; 0-4 ; 6 years) on whom home videos were available from before their disorders were noticed, dividing the records into three periods (Period I : 0 ; 0-0 ; 6 years, Period II : 0 ; 7-1 ; 0 years, Period III : 1 ; 1-2 ; 0 years). As results, it was found that disturbances in social interaction and emotional disorders were observable before 0 ; 6 years, and noted in all cases after 1 ; 1 years. Disorders in visual and auditory behavior were seen from 0 ; 3 years, including distinctive perceptual behavior. Disorders in muscle tonus and motor function were seen past 0 ; 7 years, and atypical behavior after 0 ; 9 years.This study has provided a valuable key to early detection, although further comparative analysis against other developmental disorders and normal subjects are in order.

通过观察婴儿的行为，进行了以下两项研究，以提取自闭症的早期症状：1）使用检查表的评估：使用24项检查表评估两组受试者：188例自闭症儿童（146名男孩，42名女孩; 6.7 <plus-minus>± 3.5岁）和261例正常对照受试者（133名男孩，128名女孩; 1.8 <plus-minus>± 0.8岁）。Logistic回归分析将结果分为四个水平（I-IV）。I级项目与孤独症诊断的相关性最高，但IV级以下的行为被认为在早期SI方面具有深刻的意义2）录像分析：8例病例进行了录像评估（男孩，首次就诊时的年龄：2岁; 0-4岁; 6岁），在注意到他们的疾病之前可以获得家庭录像，将记录分为三个时期（第一阶段：0 ; 0-0 ; 6年，第二阶段：0 ; 7-1 ; 0年，第三阶段：1 ; 1-2 ; 0年）。结果发现，社会交往和情绪障碍的干扰是可观察到的0 ; 6年前，并指出在所有情况下，1 ; 1年后。视觉和听觉行为障碍，从0 ; 3年，包括独特的感知行为。肌肉紧张性和运动功能障碍被认为是过去的0 ; 7年，和非典型行为后0 ; 9 years.这项研究提供了一个有价值的关键，早期发现，虽然与其他发育障碍和正常人的进一步比较分析是有序的。