权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Development of a new-therary for spastic dysphonia

痉挛性发声障碍新疗法的开发

基本信息

批准号：
04671038
负责人：
KOJIMA Hisayoshi
金额：
$ 1.28万
依托单位：
KYOTO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1993
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04671038/
关键词：
Spastic dysphonia Resection of false vocal cord Supra laryngeal pressure Articulation Plosive sound Ficative sound 声道咽頭圧高速度ビデオカメラ

项目摘要

The purpose of this project is to develope a new therapy for spastic dysphonia, whose definite etiology and effective treatment is not established. To examinie the relationship between the supralaryngeal pressure and vocal vibration, we investigated how the suprastructure of larynx influenced the vocal cord vibration by the extracted canine larynx. The result was that vocal vibration stopped immediately after supralaryngeal structure constricted and the pressure increased, and re-vibration was observed soon after supralaryngeal relaxation began and the pressure decreased. We suspected that this phenomenon meant constriction of supralaryngeal structure obstructed the regular vocal vibration and constriction of supralaryngeal structure compared to abduction of false vocal cord in spastic dysphonia. Based on this speculation, we thought resection of false vocal cord might improve spastic phonation. Resection of false vocal cord was applied to three patients. As the result, some improvement was obtained in two patients and spastic phonation didn't change in the other. The failed reason was that not only supralaryngeal pressure but many factors, such as articulation system and respiratory function may relate the etio]ogy of spastic dysphonia. Furthermore, we tried to elucidate the regulation mechanism of laryngeal adjustment in the running speech in normal candidate by high speed video. In voiceless plosive sound, stop of vocal vibration is regulated by the increased supralaryngeal pressure and in voiceless fricative sound, stop of vibration was controlled by intralary ngeal muscles. This result may be helpful in the study of articulatioin disorder in the near future.

本课题的目的是为痉挛性发声障碍开发一种新的治疗方法，其确切的病因和有效的治疗方法尚未建立。为探讨喉上压与声带振动的关系，我们用离体犬喉观察了喉上结构对声带振动的影响。结果表明，喉上结构收缩、压力升高后，声带振动立即停止，喉上结构松弛、压力降低后，声带振动很快恢复。我们怀疑这种现象意味着与痉挛性发声障碍的假声带外展相比，喉上结构的收缩阻碍了正常的发声振动和喉上结构的收缩。基于此推测，我们认为切除假声带可能改善痉挛性发声。3例行假声带切除术。结果，两例患者的痉挛性发音得到了一定的改善，另一例患者的痉挛性发音没有改变。失败的原因是痉挛性发声障碍的病因不仅与喉上压有关，还与发音系统、呼吸功能等多种因素有关。此外，我们还试图通过高速视频来阐明正常候选人连续言语中喉部调节的调节机制。在无喉塞音中，声带振动的停止是由喉上压力的增加所调节的，而在无喉塞音中，声带振动的停止是由喉内肌所控制的。这一结果可能有助于今后对关节紊乱的研究。