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Development and Clinical Application of the Internal Fixation System and Cervical Spinal Prosthesis for Cervical Spinal Reconstruction

颈椎重建内固定系统及颈椎假体的研制及临床应用

基本信息

批准号：
05807131
负责人：
ABUMI Kuniyoshi
金额：
$ 1.02万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1993
资助国家：
日本
起止时间：
1993 至 1994
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05807131/
关键词：
Cervical Spine Spinal Fixation Artificial Vertebral Body Pedicle 頸椎

项目摘要

1. Anatomical Research of the Cervical Spine : Using the human cervical vertebrae, morphological studies were conducted. Size of the cervical pedicle in Japanese, have not been reported, was investigated. The results were used for the development of the cervical internal fivation system.2. Biomechanical Research of the Dynamics of the Cervical Spine : Cineradiographs were obtained from healthy young adults and from the patients with unstable cervical spinal segment. It had been revealed that there were time phase lag in flexion-extension motion of the cervical spine. Flexion motion start edin upper motion segments in healthy, and started in unstable motion segment in the patients with unstable segments.3. Development and Biomecanical Study of the Cervical Internal Fixation System : Neuw transpedicular screw fixation system, with screw diameter of 3.5mm, 4.0mm and 4.5mm was develped based on the anatomical study. Biomechanical test revealed that strength of the system was sufficient for clinical use.4. Clinical Research of the Cervical Internal Fixation System : Results of the clinical application of the developed transpedicular screw fixation system revealed that the system was safe enougn for clinical use and applicable for reconstructive surgery of the cervical spine with instability.5. Development of the Cervical Spinal Prosthesis : Newly designed cervical prosthesis for the cervical vertebral body using AW-Glass Ceramic was deviloped. The safety was proved through the long term follow-up study of thoraco-lumbar prosthesis using the same material.

1.颈椎的解剖学研究：以人颈椎为研究对象，对颈椎进行了形态学研究。调查了日本人颈椎椎弓根的大小，但尚未见报道。研究结果为颈椎内固定系统的研制奠定了基础。颈椎动力学的生物力学研究：电影X线片取自健康青年和颈椎节段不稳患者。结果表明，颈椎前屈后伸运动存在时相滞后。正常人屈曲运动始于上位运动节段，不稳定节段患者屈曲运动始于不稳定运动节段。颈椎内固定系统的研制及生物力学研究：在解剖学研究的基础上，研制了Neuw椎弓根螺钉固定系统，螺钉直径分别为3.5 mm、4.0 mm和4.5 mm。生物力学测试表明，该系统强度满足临床使用要求。颈椎内固定系统的临床研究：研制的经椎弓根螺钉内固定系统的临床应用结果表明，该系统是安全的，可用于颈椎失稳的重建手术。颈椎假体的研制：采用AW-玻璃陶瓷研制了新型颈椎假体。通过使用相同材料的胸腰椎假体的长期随访研究，证明了该材料的安全性。