Biomechanical Research for Rigidity and Stability of the Metastatic Thoracic and Lumbar Spine

1. 胸椎转移形态的影像学研究：应用CT、x线平片和层析片探讨椎体转移部位与临床稳定性的关系。因此，胸椎关节对转移性胸椎稳定性的重要性是明确的。胸椎关节对胸椎稳定的生物力学研究：一项生物力学研究表明椎间盘和胸椎关节对胸椎稳定具有重要作用。利用溶骨胸椎转移模型研究转移性胸椎刚度的生物力学研究：利用转移性脊柱模型研究椎体转移延伸与脊柱稳定器破坏的关系。转移灶的延伸与转移脊柱的刚性呈负相关。椎体关节的破坏显著影响转移性胸椎的稳定性。转移性胸椎的失效负荷受椎体转移灶的延伸和肋椎关节的破坏的影响。

1. Radiological research of metastatic pattern in the thoracic spine: Relation between location of vertebral metastasis and clinical stability was investigated using CT, plain X-ray films and laminographs. As the result, importance of the costvertebral joint for stability of metastatic thoracic spine was definite.2. Biomechanical research regarding the costvertebral joint for thoracic spinal stability: A biomechanical study revealed that the intervertebral disc and the costvertebral joint have important role for the thoracic spinal stability.3. Biomechanical research of rigidity of metastatic thoracic spine using osteolytic thoracic spinal metastatic model: Relation between extend of the vertebral body metastasis and destruction of the spinal stabilizers was investigated using metastatic spinal model. There was negative correlation between extend of metastatic lesion and rigidity of the metastatic spine. Destruction of the costvertebral joint affect significantly on the stability of the metastatic thoracic spine. Failure load of the metastatic thoracic spine was affected by extend of the metastatic lesion of the vertebral body and destruction of the costvertebral joint.