Two-dimensional gas chromatography system, coupled to olfactometry, flame ionization detector as well as a time of flight mass spectrometer.

对于感官科学（例如香气和气味表征、代谢物谱）、食品化学（例如反应性食品成分、脂质组学）和地质学（例如水生生物化学过程的挥发性成分）领域的大量正在进行的和应用的项目中的全面样品分析，需要强大的无定向分析。使用GCxGC-ToF-MS进行分析是必不可少的，以便根据最新技术水平分析相应的样品提取物并获得最佳分离结果。这对于研究小组目前可用的心脏切割系统是不可能的，因为这些系统只能通过两个柱分离选定的洗脱液，这就是为什么目标化合物分析是这里的主要焦点。然而，这些系统的灵敏度和分辨率不适合样品筛选（非目标分析），特别是痕量组分。GCxGC调节允许分离具有共洗脱分析物的复杂提取物。由于高分辨率与多元数据分析的有用应用相结合，可以检测具有复杂成分的样品之间的统计差异。样品组成可以在其完整的复杂性和未知的活性成分可以定性和定量评估。特别是，对于作为感官科学分析的一个组成部分的“挥发物组学”和“代谢组学”领域的计划研究活动，这种技术与飞行时间质谱仪（ToF-MS）相结合是先决条件。通过在FAU实验室实施GCxGC-ToF-MS技术，将创建非目标分析的要求。这对于食品化学（食品安全和质量，香气和气味研究），环境科学（地质学）和职业医学的成功研究至关重要。拟议的GCxGC-ToF-MS是FAU研究所面临的几个分析挑战的理想和高度灵活的解决方案，将为国际相关科学成功的持续扩展做出重大贡献。

For a comprehensive sample analysis within a large number of ongoing and applied projects in the fields of sensory sciences (e.g. aroma and odor characterization, metabolite profiles), food chemistry (e.g. reactive food ingredients, lipidomics) and geology (e.g. volatile components of aquatic biogeochemical processes), a powerful, undirected analysis is required. An analysis using GCxGC-ToF-MS is indispensable in order to analyse the respective sample extracts according to the state of the art and to achieve optimal separation results. This is not possible with the heart-cut systems currently available in the research group, as these only separate selected eluents via two columns, which is why the target-compound analysis represents the primary focus here. However, the sensitivity and resolution of these systems is not suitable for sample screening (non-target analysis), especially for trace components. GCxGC modulation allows the separation of complex extracts with coeluting analytes. Due to the high resolution paired with the resulting useful application of multivariate data analysis, it is possible to detect statistical differences between samples with complex compositions. The sample composition can be determined in its full complexity and unknown active components can be evaluated qualitatively as well as quantitatively. Especially, for the planned research activities in the field of "volatilomics" and "metabolomics" as an integral part of analytics in the sensory sciences, this technology coupled with a time-of-flight mass-spectrometer (ToF-MS) is a prerequisite. By implementing the GCxGC-ToF-MS technology in the FAU laboratories, this requirement for non-target analytics will be created. This is essential for successful research in food chemistry (food safety and quality, aroma and odor research), environmental sciences (geology) and occupational medicine. The proposed GCxGC-ToF-MS is an ideal and highly flexible solution for several analytical challenges faced by research at FAU and will contribute significantly to the continuous expansion of the internationally relevant scientific success.