Coordination Funds

四个站点之间的合作对于收集肝脏、铁和骨代谢方面的专业知识至关重要，这是成功开展跨区域铁ros项目所必需的。需要采取措施确保有效的协作、沟通和生成可重复数据的方法的标准化。这些措施（例如，务虚会、电话会议、网络研讨会、培训课程、网页）将由发言人和我们在此申请的协调员一起实施。协调员还将管理和实施促进性别质量的工具，如自由职业保姆服务、家庭办公用品以及在育儿假期间继续研究的灵活资金。此外，对年轻研究人员的指导和支持对于促进下一代研究人员至关重要。因此，我们将实施具体的工具（如启动资金、个人指导）来促进年轻研究人员的职业发展。FerrOs为三位临床科学家申请资助，以获得受保护的研究时间，以促进他们的科学进展，并通过在人体组织中验证小鼠的发现来促进临床转化。沿着这些思路，我们已经通过合作伙伴获得了明确的大型队列，这将允许询问人类铁和骨代谢之间的联系。这些分析应由生物信息学家与我们的合作伙伴密切沟通进行。此外，由于一些项目将产生组学数据，生物信息学家也将协助这些复杂的分析，以确保标准化的数据分析。综上所述，该项目对FerrOs的成功表现至关重要，因为所有项目合作伙伴都将从其服务中受益。

Collaboration across four sites is paramount to gather the expertise in liver, iron, and bone metabolism that is required to successfully conduct this transregional FerrOs project. Measures need to be taken to ensure efficient collaboration, communication, and the standardization of methods to generate reproducible data. These measures (e.g. retreats, teleconference calls, webinars, training course, homepage) will be implemented by the spokesperson together with a coordinator, the position for which we apply here. The coordinator will also manage and implement tools that promote gender quality such as a free-lance nanny service, home office supplies, and flexible funds to continue research during parental leave. Moreover, mentoring and support of young researchers is essential for promoting the next generation of researchers. Therefore, we will implement specific tools (e.g. start-up funding, personal coaching) to advance the careers of young researchers. FerrOs requests funding for three clinician-scientists to obtain protected research time to promote their scientific progression and foster clinical translation by validating findings in mice in human tissues. Along those lines, we have gained access to well-defined large cohorts through collaboration partners that will allow interrogating the link between iron and bone metabolism in humans. These analyses shall be performed by a bioinformatician in close communication with our collaboration partners. Moreover, as several projects will generate -omics data, the bioinformatician will also assist with these complex analyses to ensure standardized data analysis. Taken together, this project is essential for a successful performance of FerrOs as all project partners will benefit from its services.