Clinical research for relationship between periodontal disease and systemic disease

本研究的目的是确定日本牙周炎与糖尿病、动脉粥样硬化等全身性疾病之间的关系。我们与日本的13所大学合作，推进了这项研究。结果，我们得到了一些新的看法，如下。在日本，牙周炎与糖尿病有关。在日本，牙周炎也与动脉粥样硬化和其他全身性疾病有关。牙周治疗可使糖尿病病情好转到健康状态。4 .糖尿病患者手术与非手术牙周治疗效果的比较。牙周炎与高血压关系的研究。牙周细菌影响心血管疾病。日本人对牙周医学有了许多新的认识。牙周炎与全身性疾病密切相关，如糖尿病、动脉粥样硬化、低体重出生等。牙周治疗明显改善全身状况。牙周炎治疗后，糖尿病指标有所改善。在未来，我们必须继续这项研究，以确定牙周炎和全身性疾病之间的关系。我们必须在循证医学的基础上开发新的牙周炎治疗方法。

The purpose of this research is to identify the relationship between periodontitis and systemic disease such as diabetes, atherosclerosis, et al. in Japanese. We collaborated with 13 university in Japan and progressed this research. As results, we got some new views as follows.1. Periodontitis is associated with diabetes in Japanese subjects.2. Periodontitis is also associated with atherosclerosis and other systemic disease in Japanese.3. Periodontal treatment improve the diabetic condition to healthy one.4. Examination of the effects of surgery or non-surgery periodontal therapy in diabetic patients.5. Examination of relationship between paeriodontits and high blood pressure.6. Periodontal bacteria affect cardiovascular disease.We got many new views on periodontal medicine in Japanese. Periodontitis is tightly associated with systemic disease such as diabetes, atherosclerosis, low weight birth, and others. It was clear that periodontal treatment improve systemic condition. After treatment of periodontitis, diabetic index was improved.In the future, we have to continue this research to identify the relationship between periodontitis and sysytemic disease. And we have to develop new therapy of periodontitis on the basis of EBM(evidence based medicine).