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Effect of maintaining neck flexion position and periodic movement on brain activation

保持颈部屈曲位置和周期性运动对大脑激活的影响

基本信息

批准号：
17207019
负责人：
FUJIWARA Katsuo
金额：
$ 31.62万
依托单位：
Kanazawa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2007
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17207019/
关键词：
Neck flexion position Periodic movement Brain activation Attention Voluntary movement Reaction time of eve movement Prefrontal cortex Cerebral blood flow 大脳皮質局所血流量脳周波数分析頚部前屈感覚刺激誘発電位磁気刺激運動誘発電位脳波周波数分析筋血流量

项目摘要

Firstly, we investigated the brain activation caused by neck flexion and observed following findings: Facilitation of various sensory brain evoked potentials and increment of cerebral blood flows in the relevant brain regions; Increments of amplitude in contingent negative variation and preceding action time of postural muscles during bilateral arm movement; Shortening of P300 latency and increase of P300 amplitude at Pz site during the arm movement; Decrease in negative peak amplitude at Cz cite associated with the anti-saccade; Increase in motor evoked potentials recorded from the upper limb muscles, elector spinae and rectus femoris by transcranial magnetic stimulation to the motor cortex. Furthermore, vibration stimulation effects to the trapezius were found for shortening of reaction times in visually-guided, memory-guided and anti saccades. The shortening of reaction times in the latter two saccades was noticeable.Next, we investigated the brain activation during saccade caused b … More y periodic movements (respiration, mastication, gait, floor oscillation, and repetitive neck flexion). Duration of the movement tasks was 2 or 3 minutes. The former 3 movements were performed in two ways: one was more automatic and another was more voluntary Floor oscillation was adopted as an automatic periodic movement, while repetitive neck flexion as a voluntary movement. Apparent brain activation was observed only for one minute after voluntary periodic movement. Particularly, high brain activation was found during antisaccade after repetitive neck flexion.Finally, we investigated training effects of brain activation caused by neck flexion and periodic movement, subjected healthy elderly adults and dementia patients. Antisaccade task or touch panel task was adopted as training for 3 weeks or one month. In the elderly, significant training effects were found in antisaccade task, especially with neck flexion, and in touch panel training. In the patients with frontal lobe atrophy, effects by touch panel training were found in antisaccade task. Less

首先，我们研究了颈部屈曲引起的脑激活，观察到以下结果：各种感觉脑诱发电位的促进和相关脑区脑血流量的增加；双侧手臂运动时体位肌偶然负变幅和前动作时间的增量手臂运动时P300潜伏期缩短，Pz部位P300振幅增加；Cz - cite负峰幅度的减小与抗扫视有关；经颅磁刺激运动皮质后，上肢肌肉、脊柱和股直肌的运动诱发电位增加。此外，振动刺激对斜方肌的影响可以缩短视觉引导、记忆引导和抗扫视的反应时间。后两次扫视的反应时间明显缩短。接下来，我们研究了由更多周期性运动（呼吸、咀嚼、步态、地板摆动和重复颈部弯曲）引起的扫视期间的大脑激活。运动任务的持续时间为2 ~ 3分钟。前3个动作以两种方式进行：一种是更自动的，另一种是更自愿的。地板振荡是一种自动的周期性动作，而重复的颈部屈曲是一种自愿的动作。在自愿周期性运动后，仅观察到一分钟的明显大脑活动。特别是，在重复颈部屈曲后的抗眼跳期间，发现大脑高度激活。最后，我们以健康老年人和痴呆患者为研究对象，研究了颈部屈曲和周期性运动引起的脑激活的训练效果。采用3周或1个月的抗眼跳任务或触控面板任务进行训练。在老年人中，抗扫视任务（尤其是颈部屈曲）和触控板训练效果显著。在额叶萎缩患者中，触摸板训练对抗眼跳任务有一定的影响。少