Research of the Molecular Network Regulating Endochondral Ossification
Research of the Molecular Network Regulating Endochondral Ossification
批准号:
18209047
负责人:
KAWAGUCHI Hiroshi
金额:
$31.45万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2009
中文摘要
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英文摘要
We identified a transcription factor p63 as the potent inducer of SOX6, a member of SOX family essential for chondrocyte generation and differentiation. In this study, we revealed that p63 was extensively expressed in chondrocytes, that p63 was indispensable for development of limb cartilage, and that p63 played important roles in every differentiation stages of chondrocytes.
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DOI:
10.1007/s11154-006-9011-3
发表时间:
2006-06-01
期刊:
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
影响因子:
8.2
作者:
[Kawaguchi, Hiroshi]
通讯作者:
Kawaguchi, Hiroshi
Aktl in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions
小鼠软骨细胞中的 Aktl 在生理和病理条件下控制软骨内骨化过程中的软骨钙化
DOI:
--
发表时间:
2010
期刊:
Arthritis Rheum 62(3)
影响因子:
--
作者:
[Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa A, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H.]
通讯作者:
Kawaguchi H.
DOI:
10.1002/art.24243
发表时间:
2009-01-01
期刊:
ARTHRITIS AND RHEUMATISM
影响因子:
--
作者:
[Higashikawa, Akiro, Saito, Taku, Kawaguchi, Hiroshi]
通讯作者:
Kawaguchi, Hiroshi
Low dietary vitamin K intake is associated with radiographic knee osteoarthritis in the Japanese elderly : Dietary survey in a population-based cohort of the ROAD study.
膳食维生素 K 摄入量低与日本老年人的放射学膝骨关节炎相关:ROAD 研究中基于人群的膳食调查。
DOI:
--
发表时间:
2009
期刊:
J Orthop Sci 14
影响因子:
--
作者:
[Hiroyuki Oka, Hiroshi Kawaguchi, et al]
通讯作者:
et al
C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57Kip2.
C/EBPβ 通过 p57Kip2 的反式激活促进软骨细胞从增殖向肥大分化的转变。
DOI:
--
发表时间:
2009
期刊:
PLoS ONE(in press)
影响因子:
--
作者:
[Tomoo Oda, et. al., Ogasawara T et al., Asawa Y et al., Hirata M et al.]
通讯作者:
Hirata M et al.
共 72 条
Deep Learning Processor for Pipelined Backpropagation
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批准号:18H01500
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.82万
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财政年份:2018
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Autophagy mechanism in cartilage chonsrocytes.
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批准号:25670629
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2013
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Japanese Economic Thought : Time and Space
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批准号:25380256
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2013
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Stud aiming at elucidating the molecular mechanism behind spondylosis through establishing cre / lox P system in the field of intervertebral disc.
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批准号:23659706
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.25万
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财政年份:2011
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Relation between optical intrinsic signal imaging on regulation of microcirculation on mice somatosensory cortex
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批准号:22700441
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.91万
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财政年份:2010
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Strategic research for elucidation of molecular pathophysiology and identification of therapeutic target of lumbar spondylosis
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批准号:22249056
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.45万
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财政年份:2010
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Construction of a Historical GIS for Analyzing the Population Distribution in Pre-Modern Japan
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批准号:21300098
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.07万
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财政年份:2009
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Super-Low-Operating-Voltage Dependable SRAM Using Total Variability Suppression Effects in FD-SOI
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批准号:20360161
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.73万
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财政年份:2008
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Data analysis system for historical demography and genealogy in pre-modern Japan
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批准号:18500198
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2006
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Elucidation of molecular mechanism involved in mechanical stress signaling in bone - functional analysis, contribution to pathology, and cloning of related molecule of a novel gene Znt5 -
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批准号:15390451
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.41万
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财政年份:2003
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Mechanism of regulation of bone and cartilage metabolism by fibroblast growth factor-18 (FGF-18)
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批准号:12470303
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.34万
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财政年份:2000
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Stimulatory effects of fibroblast growth facor-2 on bone formation and bone resorption
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批准号:09307033
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$15.94万
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财政年份:1997
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Stereochemistny and Reactivity of the Complexes with Co-C bond Obtained by Photodecarboxylation
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批准号:08454211
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.9万
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财政年份:1996
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负责人:KAWAGUCHI Hiroshi
-
依托单位:
Study on Mass Spectrometry for Nonmetallic Elements with Reduced-Pressure ICP
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批准号:08455387
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.69万
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财政年份:1996
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Radio-Frequency Glow-Discharge Mass Spectrometry for Direct Analysis of Sintered Ceramics
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批准号:04650677
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.09万
-
财政年份:1992
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负责人:KAWAGUCHI Hiroshi
-
依托单位:
Mechanism of Coordination-site Exchange Reaction of the Cobalt(III) Complexes Containing Multidentate Ligands
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批准号:02640481
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
-
财政年份:1990
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负责人:KAWAGUCHI Hiroshi
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依托单位:
Mechanism of Interference Effects by Matrix Element and Elimination of the Effect in ICP Mass Spectrometry
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批准号:01550573
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
-
财政年份:1989
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负责人:KAWAGUCHI Hiroshi
-
依托单位: