Implementation of intelligent integrated bio-imaging system

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We devised an intelligent bio-imaging device (IID) consisting of a charge-coupled device (CCD) chip and Field programmable Gate Array (FPGA) circuits. IID is able to not only capture the bio-images but also calculate the locations and patterns of fluorescent changes in the image. Mounting IID and a multi-electrode stimulation apparatus on the microscope, we developed a prototype of novel bio-assay system with which we can automatically give feedback stimulations on nervous and muscle tissues in real time to study their physiological properties.