Measurements and analysis of fluctuations in cellular systems
Measurements and analysis of fluctuations in cellular systems
批准号:
19207012
负责人:
SAKO Yasushi
金额:
$32.86万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
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英文摘要
Fluctuations of biological reactions were measured and analyzed for dynamics of proteins, reactions of molecular systems, and cell behaviors in the EGF-Ras-MAPK system, which is a cell signaling network. Intramolecular dynamics and translational movements of EGF receptor and RAF ; reaction dynamics between EGF receptor and Grb2, Ras and RAF, and MAPKK and MAPK ; and fluctuations of cell fate decision that occurred spontaneously and in response to EGF and NGF have been studied.
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細胞内シグナル伝達システムの1分子イメージング
细胞内信号系统的单分子成像
DOI:
--
发表时间:
2008
期刊:
実験医学増刊 26
影响因子:
--
作者:
[T.Oba, P.Sun, Y.Harada, T.Takahashi, H.lriuda, M.Seki, Y.Nakanishi, S.Noguchi, T.lshida, and M., 佐甲靖志]
通讯作者:
佐甲靖志
全反射顕微鏡と1分子計測「生細胞蛍光イメージング」原口徳子、木村宏、平岡泰編
全内反射显微镜和单分子测量“活细胞荧光成像”编者:Noriko Haraguchi、Hiroshi Kimura、Yasushi Hiraoka
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Gorbacheva, L., et al., 小柳光正, 加藤勝, 佐甲 靖志]
通讯作者:
佐甲 靖志
細胞内1分子計測とシステムズバイオロジー
细胞内单分子测量和系统生物学
DOI:
--
发表时间:
2010
期刊:
細胞工学
影响因子:
--
作者:
[日比野佳代, 他]
通讯作者:
他
DOI:
10.1016/j.bpj.2009.05.048
发表时间:
2009-09-02
期刊:
BIOPHYSICAL JOURNAL
影响因子:
3.4
作者:
[Hibino, Kayo, Shibata, Tatsuo, Sako, Yasushi]
通讯作者:
Sako, Yasushi
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Ueda, et al.]
通讯作者:
et al.
共 28 条
Direct observation of single particle movements in the cytoplasm
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批准号:25600051
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
-
财政年份:2013
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负责人:SAKO Yasushi
-
依托单位:
Raman spectrum analysis of cell differentiation dynamics
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批准号:23650280
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2011
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负责人:SAKO Yasushi
-
依托单位:
Single-molecule analysis of the spatio-temporal properties of cell signaling processes by small GTPases.
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批准号:15310092
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.83万
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财政年份:2003
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负责人:SAKO Yasushi
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依托单位:
Development of an in vivo single-molecule fluorescence microscope and its application to the studies of cell signaling
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批准号:12558082
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.77万
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财政年份:2000
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负责人:SAKO Yasushi
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依托单位:
Development of the single-molecule technique to visualize protein-protein interactions in living cell and its application to the studies of cell signaling
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批准号:11480210
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.81万
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财政年份:1999
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负责人:SAKO Yasushi
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依托单位:
Development of Super Sensitive Position Detector and Its Application on the Studies of Plasma Membrane Proteins
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批准号:08558075
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$5.7万
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财政年份:1996
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负责人:SAKO Yasushi
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依托单位:
Domain structure of the plasma membrane : interaction between membrane skeleton and membrane receptors
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批准号:04833003
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1992
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负责人:SAKO Yasushi
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依托单位:
海外基金