Analysis of virulence factors in cariogenic bacteria for cardiovascular diseases

已知变形链球菌是一种主要的致龋细菌，在血液中也可能表现出毒性。血清型k菌株是口腔中存在的一种次要血清型，在血液中可能表现出较高的毒力，因为主要细胞表面抗原缺陷导致的抗原性较低，导致菌血症持续时间较长。此外，在该菌株中发现的具有胶原结合特性的生物体的较高比率也可能与暴露的内部胶原组织对血管内皮的毒性有关。

Streptococcus mutans is known to be a major cariogenic bacterial species that may also show virulence in blood. Serotype k strains, a minor serotype present in the oral cavity, may show higher levels of virulence in blood, because of a longer duration of bacteremia due to lower antigenicity derived from defects of major cell surface antigens. In addition, the higher rate of the organisms with collagen-binding properties identified in this strain may also be associated with virulence toward blood vessel endothelia with exposed internal collagen tissue.