RESEARCH ON PREDICTION OF PERIODONTAL DISEASE IN CHILDREN AND ADOLESCENTS

儿童和青少年牙周疾病的预测研究

基本信息

  • 批准号:
    11557165
  • 负责人:
  • 金额:
    $ 8.45万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    1999
  • 资助国家:
    日本
  • 起止时间:
    1999 至 2002
  • 项目状态:
    已结题

项目摘要

The pathogenesis of periodontitis is generally accepted to be initiated by specific bacteria, however, the occurrence rate of specific periodontal bacteria in children and adolescents remains unknown. In the present study, 10 putative periodontopathic bacteria were longitudinally examined in plaque and saliva samples from 119 periodontally healthy children (2 - 15 years old) using a polymerase chain reaction method. Capnocytophaga ochracea, Capnocytophaga sputigena, and Acrinobacillus actinomycetemcomitans were frequently found in saliva, and tended to be detected in saliva for the rest of the study, whereas Porphyromonas gingivalis, Treponema denticola, and Prevotella intermedia were rarely detected. Prevotella nigrescens was more frequently detected in plaque and its prevalence increased with age. Campylobacter rectus and Eikenella corrodens were sometimes detected from both plaque and saliva, while Bacteroides forsythus was less occasionally detected in saliva. Our findings suggest that A. actinomycetemcomitans, C. ochracea, C. sputigena, P. nigrescens, C. rectus, and E. corrodens are common members of the oral microbial flora of healthy children, whereas P. gingivalis, P. intermedia, and T. denticola appear to be transient organisms.
牙周炎的发病机制通常被认为是由特定的细菌引起的,然而,儿童和青少年牙周特定细菌的发生率仍然未知。在本研究中,10个假定的牙周致病菌进行了纵向检查,从119个牙周健康儿童(2 - 15岁)的菌斑和唾液样本,使用聚合酶链反应方法。在唾液中经常发现赭色二氧化碳嗜纤维菌、生痰二氧化碳嗜纤维菌和伴放线杆菌,并且在本研究的其余时间中倾向于在唾液中检测到,而牙龈卟啉单胞菌、齿垢密螺旋体和中间普雷沃菌很少检测到。变黑普雷沃菌在菌斑中检出率较高,且患病率随年龄增长而增加。弯曲杆菌和腐蚀艾肯氏菌有时从菌斑和唾液中检测到,而拟杆菌在唾液中很少检测到。我们的研究结果表明,A. actinomycetemcomitans、伴放线菌C. ochracea、C. sputigena、P. nigrescens、C. rectus和E. corrodens是健康儿童口腔微生物植物群的常见成员,而牙龈卟啉单胞菌、中间卟啉单胞菌和T.齿垢似乎是短暂的生物体。

项目成果

期刊论文数量(12)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
T.Ooshima: "Clinical and microhiological changes in a child with rapid alueolar bone loss and refill"Journal of Dentistry for children. 69・2. 143-147 (2002)
T.Ooshima:“儿童牙髓骨快速丢失和再填充的临床和微生物学变化”《儿童牙科杂志》69・2(2002)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
OOSHIMA, T., TAKIGUCHI, M., TAMURA, M., NISHIYAMA, N.: "CLINICAL AND MICROBIOLOGOCAL CHANGES IN A CHILD WITH RAPID ALVEOLAR BONE LOSSAND REFILL"JORNAL OF DENTISTRY FOR CHILDREN. 69(2). 143-147 (2002)
OOSHIMA, T.、Takiguchi, M.、TAMURA, M.、NISHIYAMA, N.:“牙槽骨快速流失和再填充儿童的临床和微生物学变化”儿童牙科杂志。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
S.Kimura: "Periodontopathic bacterial infection in childhood"Journal of Periodontology. 73・1. 20-26 (2002)
S.Kimura:“儿童牙周病细菌感染”牙周病学杂志73・1(2002)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
S.Kimura: "Periodontopatic Bocterial Infection in childhood"Journal of Periodontology. 73. 20-26 (2002)
S.Kimura:“儿童期牙周细菌感染”牙周病学杂志。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
T.Ooshima: "Clinical and Microbiological changes in a child with rapid alveolar bone loss and refill"Journal of Dentistry for Children. 69. 143-147 (2002)
T.Ooshima:“儿童牙槽骨快速丢失和再填充的临床和微生物学变化”《儿童牙科杂志》。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

OOSHIMA Takashi其他文献

OOSHIMA Takashi的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('OOSHIMA Takashi', 18)}}的其他基金

Investigation of mechanism of systemic diseases caused by oral bacteria and development of preventive procedures
口腔细菌引起的全身性疾病的机制研究及预防措施的制定
  • 批准号:
    23390472
  • 财政年份:
    2011
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Analysis of virulence factors in cariogenic bacteria for cardiovascular diseases
心血管疾病致龋菌毒力因子分析
  • 批准号:
    19209063
  • 财政年份:
    2007
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Molecular analysis of cell surface structures of Streptococcus mutans for virulence of infective endocarditis
变形链球菌细胞表面结构对感染性心内膜炎毒力的分子分析
  • 批准号:
    16390605
  • 财政年份:
    2004
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
MOLECULAR BIOLOGICAL ANALYSIS OF SUCROSE-DEPENDENT ADHERENCE IN STREPTOCOCCUS MUTANS
变形链球菌中蔗糖依赖性粘附的分子生物学分析
  • 批准号:
    14370693
  • 财政年份:
    2002
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
The cause of dentinal defects in heritable hypophosphatemic vitamin D-resistant rickets
遗传性低磷血症维生素D抵抗性佝偻病牙本质缺损的原因
  • 批准号:
    11470450
  • 财政年份:
    1999
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Detection of anti-caries substances in oolong tea extract
乌龙茶提取物中防龋齿物质的检测
  • 批准号:
    09672102
  • 财政年份:
    1997
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of Passive Immunization System Against Dental Caries by Hen Egg Yolk Antibodies of Streptococcus Mutans.
变形链球菌鸡蛋黄抗体抗龋齿被动免疫系统的开发。
  • 批准号:
    01870089
  • 财政年份:
    1989
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Developmental Scientific Research (B).
Transmission and Establishment of Streptococcus mutans in an animal experimental system.
变形链球菌在动物实验系统中的传播和建立。
  • 批准号:
    62570915
  • 财政年份:
    1987
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)

相似海外基金

Care on the move: active travel and the everyday mobilities of children with non-visible disabilities
移动护理:非明显残疾儿童的积极旅行和日常活动
  • 批准号:
    ES/X010880/1
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Research Grant
Exploring the Impact of Clinical Diagnosis on Health and Education Outcomes for Children Receiving Special Educational Needs support for Autism
探索临床诊断对接受自闭症特殊教育需求支持的儿童的健康和教育结果的影响
  • 批准号:
    ES/Z502431/1
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Fellowship
Evaluating the effectiveness and sustainability of integrating helminth control with seasonal malaria chemoprevention in West African children
评估西非儿童蠕虫控制与季节性疟疾化学预防相结合的有效性和可持续性
  • 批准号:
    MR/X023133/1
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Fellowship
A human slice model to understand the role of fibrosis in children with bladder exstrophy
人体切片模型了解纤维化在膀胱外翻儿童中的作用
  • 批准号:
    MR/X030946/1
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Research Grant
Vaccine hesitancy DAISI (Digital Animation in Service Improvement): To increase vaccine uptake in ethnic minority perinatal women and young children.
疫苗犹豫 DAISI(服务改进中的数字动画):提高少数民族围产期妇女和幼儿的疫苗接种率。
  • 批准号:
    MR/Z503964/1
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Research Grant
Screen4SpLDs - Development of an Automated Pre-Screening Tool for Specific Learning Disabilities in Children.
Screen4SpLDs - 开发针对儿童特定学习障碍的自动预筛查工具。
  • 批准号:
    EP/Y002121/1
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Research Grant
Exploring the Mechanisms of Multimodal Metaphor Creation in Japanese Children
探索日本儿童多模态隐喻创造的机制
  • 批准号:
    24K16041
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
Improving Flexible Attention to Numerical and Spatial Magnitudes in Young Children
提高幼儿对数字和空间大小的灵活注意力
  • 批准号:
    2410889
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Continuing Grant
The costs and benefits of an empty nest: A longitudinal study of couples' relationship functioning when children leave the home
空巢的成本和收益:对孩子离开家时夫妻关系运作的纵向研究
  • 批准号:
    2336235
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Continuing Grant
Counter-COVID public policies and the impacts on Australian children
抗击新冠疫情的公共政策及其对澳大利亚儿童的影响
  • 批准号:
    DP240101102
  • 财政年份:
    2024
  • 资助金额:
    $ 8.45万
  • 项目类别:
    Discovery Projects
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了