A clinical study of octacalcium phosphate collagen composite

磷酸八钙胶原复合物的临床研究

• 批准号: 21800004
• 负责人: KAWAI Tadashi
• 金额: $ 1.7万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21800004/
• 关键词: OCP; 骨再生; 骨質評価; Co1

We investigated whether newly formed bone conducted by implanting octacalcium phosphate (OCP) collagen composite (OCP/Collagen) in rat calvaria defect is capable of bringing osseointegration around titanium implant if placed in the re-created calvaria defect in the newly formed bone. Micro CT indicated that titanium disk connected smoothly with newly formed bone conducted by OCP/Collagen and histological analysis showed that titanium disk contacted with the newly formed bone by OCP/Collagen.

我们研究了通过在大鼠颅骨缺损中植入磷酸八钙（OCP）胶原复合物（OCP/胶原蛋白）进行的新形成的骨，如果将其放置在新形成的骨中重建的颅骨缺损中，是否能够在钛植入物周围带来骨整合。显微CT显示钛盘与OCP/Collagen新生骨顺利连接，组织学分析显示钛盘通过OCP/Collagen与新生骨接触。

项目成果

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