Study of well-defined oligosaccharide clusters for understanding their biomolecular recognition mechanisms

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Oligosaccharides form clusters on cell membranes and thereby play unique and vital roles in various cellular events through interactions with biomolecules. For the elucidation of the underlying mechanisms of the glycocluster functions, systematic methods by using NMR spectroscopy were developed. This line of study can be extended to detailed analyses of structures, dynamics, and interactions of the sugar clusters on membranes.