Fixation of traumatic pubic symphysis disruption using a new cable implant system: pre-clinical assessment of a 3D printed prototype

在医学创新的跨学科方法中，解剖学和整形外科部门提议与增材生产中心合作开发一种新的电缆植入系统，用于治疗耻骨联合创伤性中断。本项目旨在通过纳入耻骨联合的经闭孔线缆固定，创建当前金标准耻骨联合钢板的替代方案。线缆固定旨在避免与当前治疗标准相关的常见并发症（植入物松动、植入物失效）。协作、多学科的概念允许在一个项目中进行植入物开发和制造、尸体标本的临床应用评价以及植入物特征的生物力学测试。在数字规划之后，将使用称为冷金属融合的3D打印技术来创建植入物原型。然后可以通过在人尸体骨盆中的应用来测试该植入物的安全操作技术。最后，生物力学评价应允许深入了解新植入物在合成骨和人骨中的材料特性和长期稳定性。对提议的线缆植入物的最终分析可以为可能的前瞻性临床研究和骨盆损伤治疗的现代未来铺平道路。

In an interdisciplinary approach to medical innovation, the departments of Anatomy and Orthopedic Surgery propose the collaboration with the Center for Additive Production to develop a new cable-implant-system for the treatment of the traumatic disruption of the pubic symphysis. This project aims to create an alternative to the current gold-standard symphyseal plating by including a trans-obturator cable fixation of the pubic symphysis. Cable fixation is an attempt at avoiding common complications associated with the current treatment standard (implant loosening, implant failure). A collaborative, multidisciplinary concept allows implant development and manufacturing, evaluation of the clinical application in cadaver specimens, and biomechanical testing of the implant characteristics within one project. After the digital planning, a 3D printing technology called cold-metal-fusion will be used to create an implant prototype. This implant can then be tested for safe operating techniques through the application in human cadaver pelvises. Finally, a biomechanical evaluation should allow insight into material properties and the long-term stability of the new implant in synthetic and human bone. The final analysis of the proposed cable implant could pave the way to possible prospective clinical studies and a modern future in the treatment of pelvic injuries.