A systematic review and network meta-analysis of technology-based interventions for improving childhood immunization in low- and middle-income countries

基于技术的干预措施（tbi），如使用电话、短信和智能手机应用程序的干预措施，在世界范围内广泛用于提高常规疫苗接种覆盖率和及时性。然而，这些技术是否能够证明对公共卫生系统的投资物有所值，特别是在资源有限的情况下，人们知之甚少。该项目的关键科学问题是评估tbi在提高儿童免疫覆盖率和及时性方面的影响及其成本效益。为了回答这一问题，将进行系统回顾和网络荟萃分析，以综合信息并建立证据基础，证明tbi在提高低收入和中等收入国家免疫覆盖率方面的有效性和成本效益。在第一年的第一阶段，进行了全面的电子数据库（PubMed、Web of Science和EBSCOhost）搜索，以确定相关文章。共查明了11,962件有关物品。在丢弃重复的8290篇文章后，进行了标题和摘要筛选。聘请两名独立审稿人根据PICOS框架和纳入标准对审稿进行筛选。此外，我们已经在PROSPARRO中注册了我们的协议。

Technology-based interventions (TBIs) such as those using phone call, text messages, and smartphone apps are widely used for improving routine vaccination coverage and timeliness worldwide. However, little is known if these technologies demonstrate value for money to justify investment in public health systems, particularly in resource constrained settings. The key scientific questions of this project are evaluating the impact of TBIs in increasing childhood immunization coverage and timeliness and their cost-effectiveness. In order to answer this question, a systematic review and network meta-analysis will be conducted to synthesize information and create an evidence base on effectiveness and cost-effectiveness of TBIs in improving immunization coverage in low- and middle- income countries (LMICs).In the first phase of the first year, a comprehensive electronic database (PubMed, Web of Science, and EBSCOhost) search has been performed to identify the relevant articles. A total of 11,962 relevant articles have been identified. After discarding the duplicate 8,290 articles were identified for title and abstract screening. Two independent reviewers were hired to screen the review based on the PICOS framework and inclusion criteria. In addition, we have registered our protocol in the PROSPARRO.