Development of Japanese Health Risk Evaluation Model due to the Environmental Pollution and Their Exposure through Food and Feed

日本环境污染及其通过食品和饲料暴露的健康风险评估模型的开发

• 批准号: 10450196
• 负责人: MORISAWA Shinsuke
• 金额: $ 8.58万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-10450196/
• 关键词: Environmental fate; Exposure analysis; Risk evaluation model; Radioactive fallout; DDT; Human health risk; Dietary exposure; Food; feed import; 食品汚染; 放射性核種; 重金属; 食糧自給率; 環境モニタリング; 食糧貿易

The total health risk evaluation framework was developed for the reference Japanese, due to the exposure to the environmental micro-pollutants, by integrating the dynamic performance/fate evaluation model, the external exposure evaluation model through dietary and respiratory pathways considering the food/feed import, and the health risk evaluation model. The framework was applied to the global scale radioactive fallouts, the lead and benzene in gasoline, the agrochemical DDT and other pollutants.Dynamic performances of fallout radionuclides (Sr-90 and Cs-137) were evaluated for their cancer induction risks of the reference Japanese, to show quantitatively that the risk has been reduced since early 1970's, that the sr-90 related leukemia induction risk is larger than the Cs137 related risk, and that the risk is larger for the elder Japanese because of the lifetime accumulation of continuous exposure effect.Lead and benzene once contained in gasoline, and widely used DDT were evaluated for their health risk to the Japanese. The health risk due to the exposure through respiratory and dietary pathways was evaluated and the effect of the risk reduction options was compared.

通过集成动态性能/命运评估模型、考虑食品/饲料进口的饮食和呼吸途径的外部暴露评估模型和健康风险评估模型，建立了供参考日本人参考的环境微污染物暴露总体健康风险评估框架。将该框架应用于全球范围的放射性尘埃、汽油中的铅和苯、农用化学物质滴滴涕等污染物，对放射性尘埃(锶-90和Cs-137)的致癌风险进行了动态评估，定量地表明，自20世纪70年代初S以来，放射性尘埃的致癌风险有所降低，与锶-90相关的白血病诱发风险大于与Cs137相关的风险，而且由于持续暴露效应的终身积累，日本老年人的风险更大。铅和苯曾经包含在汽油中，广泛使用的滴滴涕对日本人的健康风险进行了评估。评估了通过呼吸道和饮食途径暴露的健康风险，并比较了降低风险方案的效果。

项目成果

S.Morisawa, M.Yoneda, A.Nakayama: "Quantitative Analysis of Solid Waste Treatment after the Severe Disaster with the Functional Recovery of Waste Management System and the Temporal Systems Development"Proceedings of the 2^<nd> Seminar of JSPS-MOE Core Uni

S.Morisawa、M.Yoneda、A.Nakayama：“严重灾难后固体废物处理的定量分析、废物管理系统的功能恢复和时间系统开发”JSPS-MOE第二届研讨会论文集

S.Morisawa,Y.Shimada & M.Yoneda: "Flow,Stock and Destination of Radioactive Fallout Cs-137 in the Global Environment"Water Science and Technology. Vol.42,No.7-8. 155-162 (2000)

森泽S、岛田Y

S.Morisawa,M.Yoneda 他1名: "Flow, Stock and Destination of Radioactive Fallout Cs-137 in the Global Environment"IWA Ecohazard'99 Proceedings. 223-228 (1999)

S. Morisawa、M. Yoneda 和其他 1 人：“全球环境中放射性尘埃 Cs-137 的流动、存量和目的地”IWA Ecohazard99 论文集（1999 年）。

森澤眞輔,日高大彰,米田稔: "ガソリンの無鉛化による健康リスク低減効果の評価"土木学会地球環境シンポジウム講演論文集. 第8巻. 283-288 (2000)

Shinsuke Morisawa、Daiaki Hidaka、Minoru Yoneda：“无铅汽油降低健康风险效果的评估”日本土木工程师学会全球环境研讨会论文集 8. 283-288 (2000)。

中山亜紀, 野口芳弘, 小吉省吾, 八木孝司, 森澤眞輔: "ベンゼンによる染色体異常誘発リスク評価手法の構築"環境衛生工学研究. 15. 170-174 (2001)

Aki Nakayama、Yoshihiro Noguchi、Shogo Kokichi、Takashi Yagi、Shinsuke Morisawa：“开发用于评估苯引起的染色体畸变诱导风险的方法”环境卫生工程研究 15. 170-174 (2001)。