International Cooperative Health Risk Evaluation due to the Micro Environmental Pollutants

微环境污染物健康风险国际合作评估

• 批准号: 11691150
• 负责人: MORISAWA Shinsuke
• 金额: $ 3.33万
• 依托单位: KYOTO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11691150/
• 关键词: Health risk; International comparison; Evaluation model; India; Malaysia; Gasoline management; DDT; Environmental pollution; 環境微量汚染; 日本; 数学モデル; 体内動態; 国際機関

The targets of this international cooperative study is to make clear the characteristics of the health risk situations in Japan, India and Malaysia due to the environmental deterioration, the environmental monitoring practice and the health risk evaluation studies.In the last year of the three-years project, foreign cooperative investigators, Prof. Sharma and Prof. Aziz visited Japan at the same period from India and Malaysia respectively, to discuss on the application of the Fugasity model for the environmental fate analysis of DOT under the common and country specific situations. The Physiologically-based pharmacokinetic model was also discussed on Pb and DDT to relatethe dietary exposure of these pollutants with their accumulation on the human organ and tissues. In Japan, Lead in gasoline and agrochemical DDT were banned already in early 1970's. However the leaded gasoline has just regulated in India and Malaysia, and DDT is still used in India. The cooperative risk study will contribute very much for quantitative examination of the environmental risk management policies and their effectiveness.

本国际合作研究的目的是明确日本、印度和马来西亚因环境恶化而产生的健康风险状况的特点、环境监测实践和健康风险评估研究，在三年项目的最后一年，国外合作研究者Sharma教授和Aziz教授分别从印度和马来西亚访问日本，探讨了逸度模型在一般情况下和具体国情下DOT环境归趋分析中的应用。本文还讨论了Pb和DDT的生理药代动力学模型，以建立这两种污染物的膳食暴露与人体器官和组织蓄积之间的关系。在日本，汽油中的铅和农用化学品DDT早在20世纪70年代初就被禁止了。然而，含铅汽油在印度和马来西亚刚刚管制，滴滴涕在印度仍在使用。合作风险研究将有助于定量检验环境风险管理政策及其有效性。

项目成果

M. Yoneda, S. Morisawa, N. Takine, S. Fukuhara, H. Takeuchi, T. Hirano, H. Takahashi & Y. Inoue: "Groundwater Deterioration Caused by Induced Recharge, Field Survey and Verification of the Deterioration Mechanism by Stochastic Numerical Simulation"Water,

M.米田、S.森泽、N.泷根、S.福原、H.竹内、T.平野、H.高桥

S. Morisawa, H. Hidaka & M. Yoneda: "Historical Review of Health Risk Aspects with the Leaded Gasoline Regulation in Japan, Based on the PBPK Model"Jour. of Global Environment Eng.. Vol.7. .63-78 (2001)

S.森泽、H.日高

S.Morisawa, M.Yoneda, A.Nakayama: "Quantitative Analysis of solid Waste Treatment after the Severe Disaster with the Functional Recovery of Waste Management System"Proceedings of the 2nd Seminar of JSPS-MOE Core University Program on Urban Environment. Vo

S.Morisawa、M.Yoneda、A.Nakayama：《严重灾害后固体废物处理与废物管理系统功能恢复的定量分析》JSPS-教育部城市环境核心大学项目第二次研讨会论文集。

S.Morisawa, A.Kato, M.Yoneda, Y.Shimada: "The Dynamic Performances of DDTs in the Environment and Their Exposure to Japanese : A Historical Perspective after the Ban, Journal of Risk Analysis"Journal of Risk Analysis. Vol.22(in press). (2002)

S.Morisawa、A.Kato、M.Yoneda、Y.Shimada：“滴滴涕在环境中的动态表现及其对日语的暴露：禁令后的历史视角，风险分析杂志”风险分析杂志。

中山亜紀, 野口芳弘, 小吉省吾, 八木孝司, 森澤眞輔: "ベンゼンによる染色体異常誘発リスク評価手法の構築"環境衛生工学研究. 15. 170-174 (2001)

Aki Nakayama、Yoshihiro Noguchi、Shogo Kokichi、Takashi Yagi、Shinsuke Morisawa：“开发用于评估苯引起的染色体畸变诱导风险的方法”环境卫生工程研究 15. 170-174 (2001)。