Development of in vitro exposure setups for experiments on nonthergal biological effects of modulated high intensity radiofrequency electromagnetic fields.

开发体外暴露装置，用于调制高强度射频电磁场的非热生物效应实验。

• 批准号: 10555129
• 负责人: TAKI Masao
• 金额: $ 8.13万
• 依托单位: TOKYO METROPOLITAN UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-10555129/
• 关键词: electromagnetic; biological effects; in vitro; exposure system; microwaves; 細胞; マイクロ波; 高周波; 電磁界

1 We developed microwave exposure systems for experiments on biological effects of microwaves in vitro. Strong internal field in the athermal condition was required as the special interest in this research was the health effect of localized exposure on the head by mobile telephone devices.2 Comb-type microelectrocles were fabricated. Cells were placed between the electrocles. A technique to place cells at proper positions was developed using a mask. This electrode system achieved the high intensity exposure on cells.3. A circular waveguide exposure system was developed. This system could expose a large number of cells in the required condition. The exposure assessment of this setup was made by means of numerical as well as experimental approaches.4 Further developments were made to improve the exposure system. A rectangular waveguide with a transversal slit was designed. This setup achieved very high intensity exposure of 30 W/kg for the input power of 1W.

1.我们研制了微波辐照系统，用于体外微波生物效应实验。在无热条件下的强内场是必需的，因为在这项研究中的特殊兴趣是局部暴露于头部的移动的电话设备的健康影响。2梳型微电极制造。将细胞置于电环之间。一种技术，将细胞放置在适当的位置，开发使用掩模。该电极系统实现了对细胞的高强度曝光.研制了圆波导曝光系统。该系统可以在所需条件下暴露大量细胞。通过数值和实验方法对该装置的曝光进行了评估。4进一步的发展是为了改进曝光系统。设计了一种带有横向狭缝的矩形波导。该设置对于1 W的输入功率实现了30 W/kg的非常高的强度曝光。

项目成果

Yoshihumi Maruyama, Kanako Wake, Soichi Watanabe, Masao Taki: "In vitro exposure setup using a rectangular waveguide with a transversal slit"Technical Report of IEICE, EMCJ. (to be presented, in Japanese). (2001)

Yoshihumi Maruyama、Kanako Wake、Soichi Watanabe、Masao Taki：“使用带横向狭缝的矩形波导的体外曝光设置”IEICE、EMCJ 的技术报告。

丸山祥史: "スリット導波管を用いた細胞用マイクロ波曝露装置"電子情報通信学会技術研究報告 環境電磁工学. (発表予定). (2001)

Yoshifumi Maruyama：“使用狭缝波导的细胞微波暴露装置”IEICE技术研究报告环境电磁工程（待提交）。

Yoshiaki Watanabe, Toshiyuki Tanaka, Masao Taki, Soichi Watanabe: "FDTD analysis of microwave hearing effect"IEEE Trans. Microwav. Theory Tech.. vol.48, no.11. 2126-2132 (2000)

Yoshiaki Watanabe、Toshiyuki Tanaka、Masao Taki、Soichi Watanabe：《微波听觉效应的FDTD分析》IEEE Trans。

Soichi Watanabe and Masao Taki: "An Improved FDTD Model for the Feeding Gap of a Thin-Wire Antenna"IEEE Microwave and Guided Wave Letters. Vol.8, No.4. 152-154 (1998)

Soichi Watanabe 和 Masao Taki：“细线天线馈电间隙的改进 FDTD 模型”IEEE 微波和导波快报。

Kanako Wake: "Analysis of induced currents in a rat exposed to 50 Hz linearly and circularly polarized magnetic fields"Bioelectromagnetics. Vol.21. 354-363 (2000)

Kanako Wake：“暴露于 50 Hz 线性和圆极化磁场的大鼠中的感应电流分析”生物电磁学。