Development of artificial valve for opening/closing hollow organs using by SMA actuators

在这个项目中，人工尿道瓣在中空器官中得到了特别的关注。具有经皮能量传输系统的SMA驱动器的人工尿道瓣已经得到了关注和发展。主要研究结果如下：(1)为了进一步提高生物相容性，防止人工尿道阀意外夹伤尿道口的问题，研制了一种新的改进型人工尿路瓣膜。通过实验室和动物实验验证了新型阀门的开启和关闭功能。(2)研制了一种电池供电的经皮能量互感器。通过引入电压调节电路对电池的耗电量进行补偿，实现了阀门稳定驱动。体外和活体动物实验表明，改进后的瓣膜和电池供电的经皮能量传输系统在控制尿液排出方面可以很好地替代尿道括约肌。

In this project, artificial urethral valves have been especially focused on in hollow organs. The artificial urethral valve using SMA actuators with transcutaneous energy transmission system have been focused on and developed. The obtained results are summarized as follows.(1) Aiming at further improvement in the biocompatibility and preventing the problem of accident pinch of urethra by the valve, a new improved valve was developed. Opening and closing functions of the new valve were verified by laboratory and animal experiments.(2) A transcutaneous energy transformer powered by batteries was developed. Stable driving of the valve can be obtained by introducing a voltage regulating circuit to compensate the electric consumption of the batteries. The energy transmission efficiency improvement by using of sinusoidal oscillation instead of rectangle oscillation was confirmed.(3) In vitro and in vivo animal experiments showed that the improved valve and the transcutaneous energy transmission system powered by batteries works well as a substitute for urethral sphincter in controlling the discharge of urine.