Development of artificial valve for opening/closing hollow organs using by SMA actuators

使用 SMA 执行器开发用于打开/关闭中空器官的人工瓣膜

• 批准号: 11555063
• 负责人: CHONAN Seiji
• 金额: $ 4.61万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11555063/
• 关键词: Shape Memory Alloy (SMA); Artificial urethral valve; Transcutaneous energy transmission system; Animal experiment

In this project, artificial urethral valves have been especially focused on in hollow organs. The artificial urethral valve using SMA actuators with transcutaneous energy transmission system have been focused on and developed. The obtained results are summarized as follows.(1) Aiming at further improvement in the biocompatibility and preventing the problem of accident pinch of urethra by the valve, a new improved valve was developed. Opening and closing functions of the new valve were verified by laboratory and animal experiments.(2) A transcutaneous energy transformer powered by batteries was developed. Stable driving of the valve can be obtained by introducing a voltage regulating circuit to compensate the electric consumption of the batteries. The energy transmission efficiency improvement by using of sinusoidal oscillation instead of rectangle oscillation was confirmed.(3) In vitro and in vivo animal experiments showed that the improved valve and the transcutaneous energy transmission system powered by batteries works well as a substitute for urethral sphincter in controlling the discharge of urine.

在这个项目中，人造尿道瓣膜特别关注于中空器官。基于SMA驱动器和经皮能量传输系统的人工尿道瓣膜已得到关注和发展。所得结果总结如下。(1)为了进一步提高生物相容性，防止瓣膜意外夹伤尿道，研制了一种新的改进瓣膜。通过实验室和动物实验验证了新型瓣膜的开启和关闭功能。(2)研制了一种由电池供电的经皮能量转换器Transformer。通过引入电压调节电路来补偿电池的耗电量，可以实现阀门的稳定驱动。证实了用正弦振动代替矩形振动能提高能量传输效率。(3)体外和体内动物实验表明，改进的瓣膜和由电池供电的经皮能量传输系统可以很好地替代尿道括约肌控制尿液的排出。

项目成果

Mami Tanaka (他5名): "Development of mechanical SMA urethral valve with transcutaneous energy transmission system"International Journal of Applied Electromagnetics and Mechanics. (印刷中).

Mami Tanaka（和其他 5 人）：“具有经皮能量传输系统的机械 SMA 尿道瓣膜的开发”《国际应用电磁学和力学杂志》（正在出版）。

M. Tanaka, et al.: "Artificial SMA valve for treatment of urinary incontinence: upgrading of valve and introduction of transcutaneous transformer"Bio-Medical Materials and Engineering. Vol. 9. 97-112 (1999)

M. Tanaka 等人：“用于治疗尿失禁的人工 SMA 瓣膜：瓣膜的升级和经皮变压器的引入”生物医学材料与工程。

長南征二,田中真美: "機能性材料の生体工学への応用"第12回「電磁力関連のダイナミックス」シンポジウム. 727-732 (2000)

Seiji Chonan、Mami Tanaka：“功能材料在生物工程中的应用”第 12 届“与电磁力相关的动力学”研讨会 727-732（2000 年）。

長南征二, 田中真美: "機能性材料の医学問題への応用"第6回日本整形外科レーザー研究会講演抄録集. 13-14 (2001)

Seiji Chonan、Mami Tanaka：“功能材料在医疗问题中的应用”第 6 届日本骨科激光研究小组摘要（2001 年）。

M.Tanaka (他9名): "Artificial SMA valve for treatment of urinary incontinence : upgrading of valve and introduction of transcutaneous transformer"Bio-Medical Materials and Engineering. 9. 97-112 (1999)

M.Tanaka（和其他 9 人）：“用于治疗尿失禁的人工 SMA 瓣膜：瓣膜的升级和经皮变压器的引入”生物医学材料与工程 9. 97-112 (1999)。