Change of the response of the periodontal ligament to mechanical stimulation with aging : from the aspect of the interrelation between microvasculature and the periodontal ligament cells
随年龄增长牙周膜对机械刺激反应的变化:从微血管与牙周膜细胞的相互关系来看
基本信息
- 批准号:14370685
- 负责人:
- 金额:$ 7.04万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:2002
- 资助国家:日本
- 起止时间:2002 至 2004
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
1.The purpose was to clarify the acute microvascular reaction to mechanical stimulation especially on the interrelation between endothelial cells and white blood cells.Continuous and intermittent pressure stimulation was applied to post-capillary venule in the cheek pouch of golden hamsters. As a result, at the site just below the stimulation, rolling and adhering leukocytes especially monocytes were significantly increased.2.The purpose was to clarify the long-term morphological changes of the microvasculator under the mechanical stimulation. Continuous and intermittent pressure stimulation was applied to the dorsal skin of a hamster using a dorsal skin chamber, and observed capillaries using intravital microscopy for 7days. As a result, strong increase in the permeability was observed under the continuous stimulation. Angiogenesis was detected during the observation, and the diameter of capillaries was doubled at 7 days under the intermittent stimulation.
1.目的是阐明急性微血管对机械刺激的反应,特别是内皮细胞和白细胞之间的相互关系。对金仓鼠颊袋毛细血管后小静脉进行连续和间歇压力刺激。结果,在刺激的正下方,滚动和黏附的白细胞,尤其是单核细胞显著增加。目的是阐明机械刺激下微血管的长期形态学变化。采用背皮肤腔对仓鼠背皮肤进行连续和间歇压力刺激,活体显微镜观察7天毛细血管。结果表明,在连续增产下,渗透率明显提高。观察中发现血管新生,在间歇性刺激的第7天毛细血管直径增加了一倍。
项目成果
期刊论文数量(19)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
加圧刺激による微小血管系の形態および機能の変化-生体顕微鏡による長期的観察-
压力刺激引起的微血管形态和功能的变化 - 使用活体显微镜的长期观察 -
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Tanaka N;et al.;片桐 洋一
- 通讯作者:片桐 洋一
The effect of mechanical strain on human synovial cells in the differentiation of osteoclast
机械应变对人滑膜细胞破骨细胞分化的影响
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:K Seo;Masaki Ando et al.
- 通讯作者:Masaki Ando et al.
Microvascular response to mechanical pressure in intravital fluorescence microscopy
活体荧光显微镜中微血管对机械压力的反应
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Youichi Katagiri
- 通讯作者:Youichi Katagiri
Reaction of bone tissue of the rat calvaria during modeling in response to mechanical loading
建模过程中大鼠颅骨骨组织对机械载荷的反应
- DOI:
- 发表时间:2003
- 期刊:
- 影响因子:0
- 作者:Yasutomo Oonishi
- 通讯作者:Yasutomo Oonishi
上顎側方拡大による口蓋粘膜コラーゲン線維の変化-正常組織と瘢痕組織の比較-
上颌外侧扩张引起的腭粘膜胶原纤维的变化 - 正常组织和疤痕组织的比较 -
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Kawazoe Y;et al.;半田 麻子
- 通讯作者:半田 麻子
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
IIDA Junichiro其他文献
Current concepts in alveolar ridge augmentation for implant placement
用于种植体植入的牙槽嵴增强的当前概念
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:0
- 作者:
SEKI Junya;SATO Yoshiaki;TANGJIT Nathaphon;KANAI Takenori;KUSAKABE Toyohisa;IIDA Junichiro;Takahashi T - 通讯作者:
Takahashi T
What is the optimum force in diabetic condition?
糖尿病患者的最佳力量是多少?
- DOI:
- 发表时间:
2011 - 期刊:
- 影响因子:0
- 作者:
SEKI Junya;SATO Yoshiaki;TANGJIT Nathaphon;KANAI Takenori;KUSAKABE Toyohisa;IIDA Junichiro - 通讯作者:
IIDA Junichiro
IIDA Junichiro的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('IIDA Junichiro', 18)}}的其他基金
Responses of microvasculature to mechanical stimulation on diabetic patients
糖尿病患者微血管对机械刺激的反应
- 批准号:
25463165 - 财政年份:2013
- 资助金额:
$ 7.04万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Control of alveolar bone metabolism activity with RAP induction andLIPUS irradiation
RAP 诱导和 LIPUS 照射控制牙槽骨代谢活性
- 批准号:
23659959 - 财政年份:2011
- 资助金额:
$ 7.04万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
The role of mechanical stimulation on the angiogenesis in the periodontal ligament and the change with aging
机械刺激对牙周膜血管生成的作用及其随衰老的变化
- 批准号:
17390549 - 财政年份:2005
- 资助金额:
$ 7.04万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Aging related changes on tne reactivity of the microvasculature in the periodontal ligament for occlusal force or orthodontic force
牙周膜微血管系统对咬合力或正畸力的反应性随年龄的增长而变化
- 批准号:
12470454 - 财政年份:2000
- 资助金额:
$ 7.04万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Homeostasis of periodontal ligament : emphasis on chemotaxis of preosteoclasts due to masticatory stimulation
牙周膜的稳态:由于咀嚼刺激而强调前破骨细胞的趋化性
- 批准号:
09470468 - 财政年份:1997
- 资助金额:
$ 7.04万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Effects of occlusal force on homeostasis of microcirculation in periodontal ligament.
咬合力对牙周膜微循环稳态的影响。
- 批准号:
08457565 - 财政年份:1996
- 资助金额:
$ 7.04万 - 项目类别:
Grant-in-Aid for Scientific Research (B)