Effects of occlusal force on homeostasis of microcirculation in periodontal ligament.
咬合力对牙周膜微循环稳态的影响。
基本信息
- 批准号:08457565
- 负责人:
- 金额:$ 4.29万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:1996
- 资助国家:日本
- 起止时间:1996 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
1. We have developed an in vivo microvascular bed experimental model which produces the stimulation on a post capillary venule with mild intermittent mechanical compressions of 0.5 to 1-second intervals. This type of stimulation is assumed to be the compressions of periodontal ligament during mastication.2. We have observed the increased vascular permeability reaction and the changes of leukocyte movement in a post-capillary venule during and after mechanical compression using an intra-vital microscopy, and presented these results at 29th Scientific Congress of Korean Association of Orthodontists. We have also observed the effects of aging on the responses of microcirculation to such mechanical stimulation, and presented the results at 55th Annual Meeting of Japan Orthodontic Society.3. We have made another experiment to clarify the factors inducing these responses by means of immunohistochemical technique. As a result, we were able to detect the appearance of P-selectin, a kind of adhesion molecules, on the endothelial cells around the compressed area. We have also reported these results at 22th Annual Meeting of Japanese Society for Microcirculation.
1.我们已经开发了一种在体微血管床实验模型,该模型以0.5至1秒的间隔对毛细血管后小静脉进行轻度间歇性机械按压。这种刺激被认为是牙周膜在咀嚼过程中受到的压迫.我们已经观察到增加的血管通透性反应和白细胞运动的变化,在毛细血管后微静脉的机械压缩期间和之后,使用活体显微镜,并提出了这些结果在第29届科学大会的韩国正畸医师协会。我们也观察了年龄对微循环对这种机械刺激的反应的影响,并在第55届日本正畸学会年会上发表了结果。我们还用免疫组化技术进行了另一项实验,以阐明引起这些反应的因素。结果,我们能够检测到P-选择素,一种粘附分子,在受压区周围的内皮细胞上的出现。我们还在第22届日本微循环学会年会上报告了这些结果。
项目成果
期刊论文数量(18)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
割田博之: "加圧下の単一細静脈における白血球・内皮細胞間相互作用-加齢による影響-" 微小循環学会総会抄録集. 76 (1996)
Hiroyuki Warita:“压力下单个小静脉中白细胞和内皮细胞之间的相互作用 - 衰老的影响 -”微循环学会大会记录 76 (1996)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Junichiro Iida: "Microvascular reactions to mechanical compressin in orthodontic tooth movement." 29th.Scientific Congress of Korean Association of Orthodontists. 23-26 (1996)
Junichiro Iida:“正畸牙齿移动时机械加压的微血管反应。”
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Hiroyuki Warita: "Leukocyte-endothelium interaction in a post-capillary venule under mechanical compression -Effect of aging-" Microcirculation Annual. 13 (in press). (1997)
Hiroyuki Warita:“机械压缩下毛细血管后微静脉中白细胞与内皮细胞的相互作用 - 衰老的影响 -” 微循环年度。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Junichiro Iida: "Lcukocytc Movement Chamges in Post-caplllary Vcnule During Intermittent or continuous compressions,in The Biological Mechanisms of Tooth Movement and Craniofacial Adaptation.(Ed. Davidovich. Z)" Harvard Society for the Advancement of Orth
Junichiro Iida:“间歇性或连续压缩期间毛细血管后血管中的 Lcukocytc 运动变化,牙齿运动和颅面适应的生物机制。(Ed. Davidovich. Z)” 哈佛口腔矫形促进会
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
飯田順一郎: "Microvascular reactions to mechanical compressin in orthodontic tooth movement." 大韓国歯科矯正学会学術大会抄録集. 23-26 (1996)
Junichiro Iida:“正畸牙齿移动中机械压缩的微血管反应”,韩国正畸学会学术会议摘要 23-26 (1996)。
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IIDA Junichiro其他文献
Current concepts in alveolar ridge augmentation for implant placement
用于种植体植入的牙槽嵴增强的当前概念
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:0
- 作者:
SEKI Junya;SATO Yoshiaki;TANGJIT Nathaphon;KANAI Takenori;KUSAKABE Toyohisa;IIDA Junichiro;Takahashi T - 通讯作者:
Takahashi T
What is the optimum force in diabetic condition?
糖尿病患者的最佳力量是多少?
- DOI:
- 发表时间:
2011 - 期刊:
- 影响因子:0
- 作者:
SEKI Junya;SATO Yoshiaki;TANGJIT Nathaphon;KANAI Takenori;KUSAKABE Toyohisa;IIDA Junichiro - 通讯作者:
IIDA Junichiro
IIDA Junichiro的其他文献
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{{ truncateString('IIDA Junichiro', 18)}}的其他基金
Responses of microvasculature to mechanical stimulation on diabetic patients
糖尿病患者微血管对机械刺激的反应
- 批准号:
25463165 - 财政年份:2013
- 资助金额:
$ 4.29万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Control of alveolar bone metabolism activity with RAP induction andLIPUS irradiation
RAP 诱导和 LIPUS 照射控制牙槽骨代谢活性
- 批准号:
23659959 - 财政年份:2011
- 资助金额:
$ 4.29万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
The role of mechanical stimulation on the angiogenesis in the periodontal ligament and the change with aging
机械刺激对牙周膜血管生成的作用及其随衰老的变化
- 批准号:
17390549 - 财政年份:2005
- 资助金额:
$ 4.29万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Change of the response of the periodontal ligament to mechanical stimulation with aging : from the aspect of the interrelation between microvasculature and the periodontal ligament cells
随年龄增长牙周膜对机械刺激反应的变化:从微血管与牙周膜细胞的相互关系来看
- 批准号:
14370685 - 财政年份:2002
- 资助金额:
$ 4.29万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Aging related changes on tne reactivity of the microvasculature in the periodontal ligament for occlusal force or orthodontic force
牙周膜微血管系统对咬合力或正畸力的反应性随年龄的增长而变化
- 批准号:
12470454 - 财政年份:2000
- 资助金额:
$ 4.29万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Homeostasis of periodontal ligament : emphasis on chemotaxis of preosteoclasts due to masticatory stimulation
牙周膜的稳态:由于咀嚼刺激而强调前破骨细胞的趋化性
- 批准号:
09470468 - 财政年份:1997
- 资助金额:
$ 4.29万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
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