How do interactions between axon guidance molecules bring about directed axon growth?

轴突引导分子之间的相互作用如何实现轴突定向生长？

• 批准号: DP0558835
• 负责人: A/Prof Paul Whitington
• 金额: $ 18.7万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0558835
• 关键词: How; do; interactions; between; axon

This project deals with a fundamental, yet poorly understood biological problem at the cutting edge of international science - how axons navigate to their targets. A better understanding of this basic biological process will greatly assist the development of therapies to treat a wide range of clinical conditions in which axonal connections between neurons are disrupted by trauma or disease.

该项目涉及国际科学前沿的一个基本但知之甚少的生物学问题--轴突如何导航到其目标。更好地理解这一基本生物学过程将大大有助于开发治疗各种临床病症的疗法，其中神经元之间的轴突连接因创伤或疾病而中断。