Molecular Understanding of STOP1-regulating system in plant stress tolerance

拟南芥锌指蛋白STOP 1调控铝和质子耐受基因的转录。我们对各种植物中的直向同源基因的功能进行了研究，包括木本植物、禾本科植物和木本植物。所有植物都具有STOP1同源基因的功能蛋白，这些同源基因调控着各种酸和铝抗性基因的表达。这表明STOP1调控系统在陆地植物中普遍存在，编码苹果酸转运蛋白ALMT1的表达受到STOP1的严格调控。该基因的表达被Al激活，但也被细菌诱导子激活。前者保护根尖免受铝毒害，而后者则招募有害细菌诱导植物免疫。表明STOP1及其调控基因可能是一个在植物逆境胁迫应答中具有多重功能的模块。

STOP1, a zinc finger protein, regulates transcription of Al and proton tolerance genes in Arabidopsis. We characcterized function of orthologous genes in various plant species, including woody plants, grass plants, and bryophyte. All plants conserved functional protein of STOP1-orthologues, which regulate expression of various acid and Alresistant genes. It indicated STOP1-regulating system is ubiquitus among wide range of land plant speceis.Expression of ALMT1, encoding malate transporter, is strictly regulated by STOP1. Expression of the gene is activated by Al, but is also activated by bacterial elicitors. The former protects root tips from Al toxicity, but the latter recruites veneficial bacteria that induce plant immunity. It indecated that STOP1 and regulating genes are likely a module that has multiple function in stress registance of higher plants.