Molecular Understanding of STOP1-regulating system in plant stress tolerance

STOP1是一种锌指蛋白，在拟南芥中调控铝和质子耐受基因的转录。我们描述了不同植物物种中同源基因的功能，包括木本植物、草本植物和苔藓植物。所有植物都保守STOP1-同源基因的功能蛋白，该蛋白调节各种耐酸和耐铝基因的表达。这表明STOP1调控系统在多种陆地植物中普遍存在，编码苹果酸转运蛋白的ALMT1的表达受到STOP1的严格调控。该基因的表达被铝激活，但也被细菌激发子激活。前者保护根尖免受铝毒害，而后者则招募诱导植物免疫的脉状细菌。这表明，STOP1和调控基因可能是高等植物逆境注册中具有多种功能的模块。

STOP1, a zinc finger protein, regulates transcription of Al and proton tolerance genes in Arabidopsis. We characcterized function of orthologous genes in various plant species, including woody plants, grass plants, and bryophyte. All plants conserved functional protein of STOP1-orthologues, which regulate expression of various acid and Alresistant genes. It indicated STOP1-regulating system is ubiquitus among wide range of land plant speceis.Expression of ALMT1, encoding malate transporter, is strictly regulated by STOP1. Expression of the gene is activated by Al, but is also activated by bacterial elicitors. The former protects root tips from Al toxicity, but the latter recruites veneficial bacteria that induce plant immunity. It indecated that STOP1 and regulating genes are likely a module that has multiple function in stress registance of higher plants.