害虫抵抗性を付与する植物免疫受容体の同定

鉴定赋予害虫抗性的植物免疫受体

• 批准号: 22KF0398
• 负责人: 白須 賢
• 金额: $ 1.41万
• 依托单位: Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for JSPS Fellows
• 财政年份: 2023
• 资助国家: 日本
• 起止时间: 2023-03-08 至 2024-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22KF0398/
• 关键词: Plant immunity; PRR; bioinformatics; nematode; evolution; pattern-recognition; receptors

I investigated the origin and evolution of pattern-triggered immunity (PTI) in plants. As mentioned, plants perceive PAMPs via PRRs to activate PTI. The origin and evolution of PRRs and PTI-signaling components is unclear. I performed a large-scale comparative genomic analysis on PRRs and PTI-signaling components in 350 plant species. While RLPs are generally more ancient than RLKs, RLK families have expanded much more than RLP families. I also showed that multiple PTI-signaling components are ancient and most show limited expansion in the plant lineage. These results suggest that PRRs and PTI signaling network are ancient and likely to exist before emergence of land plants, which then have evolved to become more complex and immune-specific in land plants.

我研究了植物模式触发免疫（PTI）的起源和进化。如前所述，植物通过 PRR 感知 PAMP 来激活 PTI。 PRR 和 PTI 信号成分的起源和进化尚不清楚。我对 350 种植物的 PRR 和 PTI 信号成分进行了大规模比较基因组分析。虽然 RLP 通常比 RLK 更古老，但 RLK 家族比 RLP 家族扩张得更多。我还表明，多个 PTI 信号成分是古老的，并且大多数在植物谱系中表现出有限的扩展。这些结果表明，PRR 和 PTI 信号网络很古老，并且可能在陆地植物出现之前就已经存在，然后在陆地植物中进化得更加复杂和具有免疫特异性。