Measurement of Fluoride Distribution in Teeth

牙齿中氟化物分布的测量

• 批准号: 11559011
• 负责人: NOMACHI Masaharu
• 金额: $ 3.71万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11559011/
• 关键词: micro-beam; Fluoride distribution; Fluoride concentration; フッ素分布

Investigating the optimum fluoride concentration for the inhibition of caries may be one of key steps to know the fluoride distribution in such a micro domain as acid-resistant layer. Methods as PIGE, EPMA and SIMS can be used. Here the micro-beam PIGE was applied to obtain high position resolution.The 1.7 MeV proton beam accelerated by the TIARA single-ended accelerator at JAERI Takasaki was delivered to a micro-beam facility. The beam spot size was about 1μm with a beam current of about 100pA.A nuclear reaction ^<19>F(p, aγ)^<16>O was used for measuring fluorine density. Gamma rays of this reaction were detected with a 2" BGO detector. Proton induced X-rays were detected with a Si(Li) detector for measuring calcium density. Beam intensity was monitored with X-ray yield from a copper foil for quantitative analysis. The fluorine distribution was measured for etched and non-etched teeth. Observed fluorine concentration in the narrow area can be seen with sub-micron beam line at TIARA.It might contribute a new tool in dentistry.

研究防龋的最佳氟浓度可能是了解氟在耐酸层等微区分布的关键步骤之一。可采用PIGE、EPMA和西姆斯等方法。利用日本原子力研究所高崎TIARA单端加速器加速的1.7 MeV质子束流，通过微束流PIGE获得高位置分辨率。束流为100pA时，束斑尺寸约为1μm，用核反应^<19>F（p，aγ）^<16>O测量氟浓度。该反应的γ射线用2”BGO检测器检测。用Si（Li）探测器探测质子诱导X射线以测量钙密度。用来自铜箔的X射线产率监测束强度以用于定量分析。测量了蚀刻和非蚀刻牙齿的氟分布。在TIARA上用亚微米束线可以观察到狭窄区域内的氟浓度，这可能为牙科学提供一种新的工具。

项目成果

山本洋子,能町正治: "虫歯予防にフッ素処理、-マイクロビームで歯の内側を覗く-"放射線と産業. 86号. 22-27 (2000)

Yoko Yamamoto，Masaharu Nomachi：“预防蛀牙的氟化物治疗 - 用微束观察牙齿内部 -”《放射与工业》86 No. 22-27 (2000)。

M.Nomachi, et al.: "Development of the Measurement System of Fluoride Distribution in Teeth."TIARA Annual Report 1999. JAERI-Revie w 2000-024. 242-244 (2000)

M.Nomachi 等人：“牙齿中氟化物分布测量系统的开发”。TIARA 年度报告 1999。JAERI-Review w 2000-024。

M.Nomachi: "Development of the Measurement System of Fluoride Distribution in Teeth."TIARA Annual Report 1999, JAERI-Review. 2000-024. 242-244 (2000)

M.Nomachi：“牙齿中氟化物分布测量系统的开发”。TIARA 年度报告 1999，JAERI 评论。

M.Nomachi: "Development of the Measurement System of Fluoride Distribution in Teeth."TIARA Annual Report 1998, JAERI-Review. 99-025. 226-228 (1999)

M.Nomachi：“牙齿中氟化物分布测量系统的开发”。TIARA 年度报告 1998，JAERI 评论。

H.Yamamoto and M.Nomachi: "Preventing Caries by Fluoride Treatments"Radiation and Industry. 86. 22-27 (2000)

H.Yamamoto 和 M.Nomachi：“通过氟化物治疗预防龋齿”辐射与工业。