Presurgical evaluation of epileptic focus with MRI and magnetoencephalography (MEG) for extra-temporal lobe epilepsy surgery.

(1)分析了顽固性癫痫患者从初坡到峰峰放电期间脑磁图分析的发展。目前对脑磁图间期峰的分析使我们能够估计癫痫病灶，并预测颞叶外癫痫患者的术后癫痫发作结果。(2)功能MRI皮质制图，作为癫痫手术的术前评估视觉图像处理系统和新软件的引入，使准确的脑功能制图，如语言和视觉感知成为可能。(3)确认MRI和MEG对癫痫患者术前评估的准确性。数字脑电图工作站的引入使我们能够检查皮质电图，并通过慢性硬膜下网格进行直接皮层刺激。术前评估和网格检查的比较证实了MEG和MRI在癫痫手术中的有效性。(4) MEG和MRI结果的临床应用。在本研究中，将MEG和MRI数据输入系统工作站，并转换为术中神经导航的三维重建图像。

(1) The development of MEG analysis for intractable epilepsy patientsInterictal spike discharge was analyzed during the period from the early slope to the spike peak. The present analysis of the interictal MEG spikes enabled us to estimate epileptic focus, and predicted post-surgical seizure outcomes for extra-temporal lobe epilepsy patient.(2) Cortical mapping with functional MRI, as presurgical evaluation for epilepsy surgeryThe introduction of visual image processing system and new software made it possible to perform the accurate functional brain mapping, such as language, and visual perception.(3) Confirmation of the accuracy of presurgical evaluation with MRI and MEG for epilepsy patients.The introductions of digital EEG workstation enabled us to exam electro-corticograms, and perform the direct cortical stimulation with chronic subdural grids. The comparison between presurgical evaluations and grids examinations confirmed the usefulness of MEG and MRI for epilepsy surgery.(4)Clinical applications of both MEG and MRI results.In the present study, both MEG and MRI data were put into the system workstation, and convert to the 3D reconstruction images for intra-operative neuronavigation.