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Schistosomiasis haematobia - Studies on Hidden Morbidity

Schistosomiasis haematobia - Studies on Hidden Morbidity
血吸虫病 - 隐藏发病率的研究
批准号:
12576007
负责人:
AOKI Yoshiki
金额:
$9.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2002

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中文摘要
翻译
血吸虫感染的发病率仅通过血尿的检查和膀胱的超声检查来评估。然而,旧的论文表明,其他器官也会受到血吸虫卵的影响。最近,我们的KAP(知识、态度和行为)研究表明,患者患有膀胱癌等隐性疾病。为了解肯尼亚血吸虫病流行区社区居民膀胱癌、肝纤维化和排尿困难的发病情况,采用膀胱癌尿液细胞学检查20岁及以上村民膀胱癌发病率。在筛查的1516人中,4人细胞学阳性,6人细胞学可疑。这一数值是日本膀胱癌发病率的100倍。肝纤维化:在一个社区进行了肝脏超声检查。为诊断门静脉周围增厚,对照组采用门静脉周围支直径95百分位数。27%的人口门脉周围增厚。排尿困难:国际前列腺症状评分用于检查排尿困难症状:流行区的男生出现排尿困难症状。采用尿流量计和超声检查尿流率和残余尿量。流行区和非流行区在校男生的排尿方式无差异。结果表明,感染病毒的男孩没有膀胱功能障碍,尽管他们抱怨有任何排尿困难的症状。
英文摘要
The morbidity due to Schisdaroma haematobium infection has been exclusively assessed by the examination of haematuria and ultrasound finding of bladder. However, the old papers have indicated that other organs are affected by S. haematobioum eggs. Recently our KAP (Knowledge, Attitudes and Practices) study suggested that the patients are suffering from the hidden morbidity such as bladder cancer. The present study was attempted to examine the incidence of bladder cancer, liver fibrosis and difficulty of urination in a community of the endemic areas of schistosomiasis haematobia in Kenya.Bladder cancer Urine cytology was performed to examine the incidence of bladder cancer among the villagers aged 20 years and over. Among 1516 individuals screened, positive cytology was detected in 4 persons and equivocal cytology was detected in 6 persons. This value is100 times as high as the incidence of bladder cancer in Japan.Liver fibrosis: Ultrasonographic investigation of liver was done in a community. For diagnosis of periportal thickening the 95^<th> percentile regarding peripheral portal vein branch diameter in the control group was used. Twenty-seven percent of the population had periportal thickening. Egg output and bladder wall morbidity were associated with an increased risk of periportal thickening.Difficulty of urination: International Prostate Symptom Score was used to examine the symptom of difficulty of urination: School boys in an endemic area were suffering from any symptoms of difficulty of urination. Uroflowmeter and ultrasound were used to examine the pattern of urination and residual urine. There was no difference in urination pattern between school boys living in endemic areas and those in non-endemic area. The results suggest that infected boys have no impediment in bladder function, although they complain of any symptoms of the difficulty of urination.
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Novel strategy for control of schistosomiasis : Decoy snails that can reduce the number of miracidia reaching the intermediate snails
  • 批准号:
    19406010
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $10.73万
  • 财政年份:
    2007
  • 负责人:
    AOKI Yoshiki
  • 依托单位:
Schistosomiasis haematobia : Hidden morbidity bared on the studies on the villagers' perception of disease
Signal Transduction relevant to Cherno-klinokinesis of schistosome miracidiai toward intermediate snail host
  • 批准号:
    13670251
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.24万
  • 财政年份:
    2001
  • 负责人:
    AOKI Yoshiki
  • 依托单位:
Role of cAMP, cGMP and Ca++ in chemotaxis of Schistosome Miracidia
  • 批准号:
    11670244
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.43万
  • 财政年份:
    1999
  • 负责人:
    AOKI Yoshiki
  • 依托单位:
海外基金