Schistosomiasis haematobia - Studies on Hidden Morbidity
Schistosomiasis haematobia - Studies on Hidden Morbidity
批准号:
12576007
负责人:
AOKI Yoshiki
金额:
$9.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2002
中文摘要
由于寄生虫感染的发病率已被专门评估的血尿检查和膀胱超声发现。然而,以往的文献表明,其他器官也受到S。血细胞卵最近我们的KAP(知识,态度和实践)研究表明,患者患有膀胱癌等隐性疾病。本研究旨在调查肯尼亚血吸虫病流行区一个社区膀胱癌、肝纤维化和排尿困难的发病率。在1516人中筛选,细胞学检测阳性4人和可疑细胞学检测6人。这一数值是日本膀胱癌发病率的100倍。肝纤维化:在一个社区进行肝脏超声检查。对于门静脉周围增厚的诊断,<th>使用对照组中关于外周门静脉分支直径的95%。27%的人有门静脉周围增厚。排尿困难:采用国际前列腺症状评分(International Prostate Symptom Score)检查排尿困难的症状:流行区的男生患有任何排尿困难的症状。采用尿流计和B超检查排尿方式和残余尿。病区和非病区男生排尿方式无差异。结果表明,受感染的男孩没有膀胱功能障碍,尽管他们抱怨排尿困难的任何症状。
英文摘要
The morbidity due to Schisdaroma haematobium infection has been exclusively assessed by the examination of haematuria and ultrasound finding of bladder. However, the old papers have indicated that other organs are affected by S. haematobioum eggs. Recently our KAP (Knowledge, Attitudes and Practices) study suggested that the patients are suffering from the hidden morbidity such as bladder cancer. The present study was attempted to examine the incidence of bladder cancer, liver fibrosis and difficulty of urination in a community of the endemic areas of schistosomiasis haematobia in Kenya.Bladder cancer Urine cytology was performed to examine the incidence of bladder cancer among the villagers aged 20 years and over. Among 1516 individuals screened, positive cytology was detected in 4 persons and equivocal cytology was detected in 6 persons. This value is100 times as high as the incidence of bladder cancer in Japan.Liver fibrosis: Ultrasonographic investigation of liver was done in a community. For diagnosis of periportal thickening the 95^<th> percentile regarding peripheral portal vein branch diameter in the control group was used. Twenty-seven percent of the population had periportal thickening. Egg output and bladder wall morbidity were associated with an increased risk of periportal thickening.Difficulty of urination: International Prostate Symptom Score was used to examine the symptom of difficulty of urination: School boys in an endemic area were suffering from any symptoms of difficulty of urination. Uroflowmeter and ultrasound were used to examine the pattern of urination and residual urine. There was no difference in urination pattern between school boys living in endemic areas and those in non-endemic area. The results suggest that infected boys have no impediment in bladder function, although they complain of any symptoms of the difficulty of urination.
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会议论文
Novel strategy for control of schistosomiasis : Decoy snails that can reduce the number of miracidia reaching the intermediate snails
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批准号:19406010
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.73万
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财政年份:2007
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负责人:AOKI Yoshiki
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依托单位:
Schistosomiasis haematobia : Hidden morbidity bared on the studies on the villagers' perception of disease
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批准号:15406017
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2003
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负责人:AOKI Yoshiki
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依托单位:
Signal Transduction relevant to Cherno-klinokinesis of schistosome miracidiai toward intermediate snail host
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批准号:13670251
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2001
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负责人:AOKI Yoshiki
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依托单位:
Role of cAMP, cGMP and Ca++ in chemotaxis of Schistosome Miracidia
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批准号:11670244
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:1999
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负责人:AOKI Yoshiki
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依托单位:
Control of Ciliary Beating of Schistosomal Miracidia
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批准号:09670266
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1997
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负责人:AOKI Yoshiki
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依托单位:
Medical ecology of schistosomiasis haematobia in the developing countries : Changes which took place in a long-term control program
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批准号:09041187
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$11.9万
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财政年份:1997
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负责人:AOKI Yoshiki
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依托单位:
CILIARY BEATING OF SCHISTOSOMA MIRACIDIUM-POSSIBLE INVOLVEMENT OF CYCLIC NCLEOTIDE AND ION CHANNEL
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批准号:07670285
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.54万
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财政年份:1995
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负责人:AOKI Yoshiki
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依托单位:
Development of a simple and sensitive enzyme-linked immunosorbent assay for anti-filarial drugs
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批准号:04557023
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$3.9万
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财政年份:1992
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负责人:AOKI Yoshiki
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依托单位:
Microtubules are damaged by diethylcarbamazine, anti-filarial drug
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批准号:62570178
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.09万
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财政年份:1987
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负责人:AOKI Yoshiki
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依托单位:
海外基金