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Schistosomiasis haematobia : Hidden morbidity bared on the studies on the villagers' perception of disease

血吸虫病：村民疾病认知研究揭示的隐性发病

基本信息

批准号：
15406017
负责人：
AOKI Yoshiki
金额：
$ 8.45万
依托单位：
Institute of Tropical Medicine, Nagasaki University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

项目摘要

The present study was attempted to examine qualitatively and quantitatively the micturition caused by Schistosoma haematobium infection, and to know the efficacy of treatment on micturition in Kenya. In addition, we examined the effect of the simple and less expensive piped water supply to the community on the prevention of schistosomiasis.1. Qualitative and quantitative studies on micturition :In the endemic areas of schistosomiasis and non-endemic area, the school boys and men were examined for micturition by International Prostate symptoms Score (IPSS) and uro-flow meter. Villagers in the endemic areas showed significantly higher IPSS value. Among the indicators of uro-flow meter, high value of T-delay was noticed for school boys in the endemic areas. The men of the endemic areas showed reduced Qmax and Qave corrected by urine volume.These results indicate that villagers in the endemic areas of schistosomiasis suffer from any symptoms and signs of micturition. The boys need the longer time to start urination after they feel an urge of urination. Men were likely to present less powerful urination.2. Effect of treatment on micturition :The school boys were examined for micturition by uro-flow meter and questionnaire made by an anthropologist. The study disclosed the symptoms of micturition. For example, the patients have the pain at the end of urination. Unexpectedly, any symptoms and signs of micturition were not improved 6 months after treatment.3. Effect of piped water supply on the prevention of schistosomiasis :Community piped water provided by NGO was expected to be effective for the prevention of schistosomiasis. However, the observation on eggs in urine, human-water contact at river, and utilization of piped water by villagers did not show any effect on the prevention of schistosomiasis.

本研究试图定性和定量地检查肯尼亚血吸虫感染引起的排尿情况，并了解肯尼亚治疗排尿的效果。此外，我们还研究了向社区提供简单、廉价的管道供水对预防血吸虫病的效果。1．排尿定性和定量研究：在血吸虫病流行区和非流行区，用国际前列腺症状评分（IPSS）和尿流量计检查男学生的排尿情况。流行地区村民的IPSS值明显较高。尿流量计指标中，流行地区男学生T延迟值较高。血吸虫病流行区的男性经尿量校正后Qmax和Qave降低。这些结果表明血吸虫病流行区的村民存在排尿症状和体征。男孩们在有尿意后需要更长的时间才能开始排尿。男性可能会出现排尿无力的情况。2．治疗对排尿的影响：通过尿流量计和人类学家制作的调查问卷来检查男学生的排尿情况。该研究揭示了排尿的症状。例如，患者会出现排尿结束时疼痛。出乎意料的是，治疗6个月后排尿症状和体征均未改善。3．自来水供应对预防血吸虫病的效果：非政府组织提供的社区自来水有望有效预防血吸虫病。但尿液中虫卵、河道人水接触、村民使用自来水等情况的观察，并未发现对预防血吸虫病有任何作用。